Giant Secondary Conjunctival Inclusion Cysts

Song, J.; Finger, Paul T.; Kurli, Madhavi; Wisnicki, H. Jay; Iacob, Codrin

doi:10.1016/j.ophtha.2006.02.031

Cited by 37 publications

(7 citation statements)

References 10 publications

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“…2 Acquired conjunctival cysts occur after implantation of conjunctival epithelium in the orbit and have been described after enucleation, strabismus surgery, or retinal detachment. 3–6…”

mentioning

confidence: 99%

“…2 Acquired conjunctival cysts occur after implantation of conjunctival epithelium in the orbit and have been described after enucleation, strabismus surgery, or retinal detachment. [3][4][5][6] In this study, we describe the clinical presentation, anatomical location, and histological features of patients with congenital conjunctival cysts and compare the histological features of inflammation with those for a large group of orbital dermoid cysts.…”

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confidence: 99%

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Congenital Conjunctival Cysts of the Orbit

Wilde

Vahdani

Rose

2021

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Purpose: To evaluate the clinical presentation, anatomical location, and histological features of congenital conjunctival cysts of the orbit. The location and the histological features of inflammation in these patients were compared with those for 293 orbital dermoid cysts. Patients and Methods: Retrospective review of the clinical details, imaging, and histopathology for patients who had excision of conjunctival cysts from their orbit between 1992 and 2020; patients with a history of trauma or surgery were omitted. Results: Twelve patients (7 male; 58%) with congenital conjunctival cysts were identified, the patients presenting at an average age of 16 years (median 26; range 1–61) with a symptoms for a mean duration of 20 months (median 24; range 6–36). The commonest symptoms were peribulbar lump (6/12 patients; 50%), and eyelid swelling and blepharoptosis (6/12 patients; 50%). An orbitaxl mass was palpable in 10 patients (83%), 3 patients (25%) had mild proptosis (1–3 mm), and the cysts were most commonly located superiorly (6/12 patients; 50%) or superonasally (3/12; 25%) in the anterior half of the orbit. Imaging was performed in 7 cases, this showing an intimate relation to the common sheath of the superior rectus/levator complex in 3 patients (25%) and to the trochlea in 1 (8%). All cysts were excised completely, and no patient had postoperative complications or recurrence. Chronic mild and nonspecific inflammation was evident within the cyst wall in 7 cases (54%), but—unlike 55% of the 293 dermoid cysts—none showed granuloma formation. Conclusion: Congenital conjunctival cysts are rare and usually present with a palpable mass in the upper eyelid sulcus. A significant proportion of these cysts have an intimate relationship with the trochlea, or the superior rectus, levator palpebrae or superior oblique muscles and, to minimize the risk of postoperative diplopia or ptosis, particular care must be exercised during surgery.

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“…2 Acquired conjunctival cysts occur after implantation of conjunctival epithelium in the orbit and have been described after enucleation, strabismus surgery, or retinal detachment. 3–6…”

mentioning

confidence: 99%

mentioning

confidence: 99%

Congenital Conjunctival Cysts of the Orbit

Wilde

Vahdani

Rose

2021

Ophthalmic Plastic &Amp; Reconstructive Surgery

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“…These types of cysts have been reported to arise from dislocated epithelium below the surface of the conjunctiva or cornea secondary to trauma [ 40 ] or surgery [ 41 ]. Acquired conjunctival inclusion cysts are known to develop following surgical implantation of conjunctival epithelium [ 41 42 ]. This complication can be prevented by paying careful attention during creation and placement of the conjunctival autograft.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Safety of a Large Conjunctival Autograft for Recurrent Pterygium

Lee

et al. 2017

Korean J Ophthalmol

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Purpose: To evaluate the efficacy and safety of pterygium excision using a large conjunctival autograft for the treatment of recurrent pterygium. Methods: The medical records of 120 patients (126 eyes) with recurrent pterygium were reviewed. For each affected eye, pterygium excision with a large conjunctival autograft was performed. The graft was harvested from the superior bulbar area and measured more than 8 × 10 mm in size. Only patients who completed at least six months of follow-up were included. Postoperative clinical outcomes, recurrence rate, and complications were analyzed. Patients with any evidence of recurrence after surgery received a subconjunctival bevacizumab injection. Results: The average patient age was 56.5 ± 10.2 years, and 45 out of 120 patients were male. The mean study follow-up period was 17.7 ± 17.6 months. Most patients were satisfied with the cosmetic outcome. Postoperative visual acuity improved from 0.69 to 0.75 (p < 0.05). Postoperative refractive astigmatism and corneal astigmatism decreased by 0.55 and 2.73 diopters, respectively (p < 0.05). The postoperative recurrence rate was 4.0%, and the average recurrence period was 7.4 ± 0.6 weeks. A subconjunctival injection of 5 mg bevacizumab was performed in cases of recurrence; no progression of the pterygium was observed following the injection. Postoperative complications included 2 cases of conjunctival graft edema in 2 eyes, 5 donor site scars in 5 eyes, 13 pyogenic granulomas in 13 eyes, and a conjunctival epithelial inclusion cyst in 7 eyes. Conclusions: Pterygium excision with a large conjunctival autograft for the treatment of recurrent pterygium produced an excellent cosmetic outcome, a low recurrence rate, and minimal complications. A subconjunctival bevacizumab injection given in cases of recurrence following surgery might be effective in preventing progression of the pterygium.

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“… 26 Rarely, there may be associated bony changes and/or globe deformity 24 . One case reported punctate calcifications along the scleral border of the cyst 23,26 . On histology, CICs demonstrate a nonkeratinizing stratified squamous epithelial lining with scattered mucin-producing goblet cells 19,22,24,25 …”

Section: Congenital Epithelial Cystsmentioning

confidence: 99%

“…2.2B, C). 26 Rarely, there may be associated bony changes and/or globe deformity 24 . One case reported punctate calcifications along the scleral border of the cyst 23,26 .…”

Section: Congenital Epithelial Cystsmentioning

confidence: 99%

Cystic Lesions of the Orbit

Cameron¹,

Tong²,

Patel³

et al. 2023

International Ophthalmology Clinics

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Orbital cystic lesions encompass an array of congenital and acquired conditions with diverse aetiologies, ranging from benign, asymptomatic cysts to sight-threatening infectious or malignant disease. 1,2 They account for 14% to 21% of all orbital lesions. 2 Macroscopically, cystic lesions appear as saccular, fluid-filled structures encapsulated by a clearly demarcated wall. 1 They are commonly classified according to the cellular origin or etiology. 3,4 In a 2004 review of childhood orbital lesions, Shields and Shields 5 categorized cystic lesions by cellular origin (surface epithelium-derived, teratomatous, neural, secondary, infectious, and noncystic lesions with a cystic component). Another classification system, proposed by Kaufman et al, 6 in 1998, organizes cystic lesions by etiology; that is, congenital, acquired, or secondary cysts arising from adjacent structures. This review will expand upon the latter scheme, employing the following classifications; congenital (epithelial and nonepithelial), vascular, infectious and inflammatory, neoplastic, and miscellaneous. True cysts and cyst-like lesions, that is, those which appear cystic on imaging, will be covered, with a particular focus on the radiologic characteristics seen.Congenital lesions, such as dermoid cysts and orbital teratoma, generally present in infancy or early childhood and are usually benign; those which present later in life are more likely acquired, although lesions such as deep orbital dermoids may present in adulthood. [6][7][8] Clinical features vary depending on the size, depth, and aggressiveness of the underlying lesion. Superficial cysts often present with a painless,

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Giant Secondary Conjunctival Inclusion Cysts

Cited by 37 publications

References 10 publications

Congenital Conjunctival Cysts of the Orbit

Congenital Conjunctival Cysts of the Orbit

Efficacy and Safety of a Large Conjunctival Autograft for Recurrent Pterygium

Cystic Lesions of the Orbit

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