“…The DQ genes are duplicated and the number of DQA and DQB genes varies between haplotypes (Andersson & Rask, 1988). The DR region is composed of one DRA gene and at least three DRB loci (Andersson et al ., 1986a,b; Davies et al ., 1997). Exon2 of DRB 3 gene, in particular, has been the most widely studied class II gene as it is extremely polymorphic (Sigurdardottir et al ., 1988, 1991; van Eijk et al ., 1992; Gelhaus et al ., 1995; Sitte et al ., 1995).…”