Abstract:We report the case of a patient diagnosed with genitogluteal porokeratosis, a disorder of epidermal keratinization. The location described is extremely rare and very often late diagnosed or even misdiagnosed. Histopathology showed a typical cornoid lamella of great value to support this diagnosis. The importance of awareness of this entity by the specialist is emphasized as a differential diagnosis among genital diseases of chronic evolution and difficult treatment.
“…Treatment of this condition remains discouraging with variable responses to keratolytics, cryotherapy, 5-fluorouracil, imiquimod, calcipotriol, diclofenac, corticosteroids, topical antifungals, and lasers [1,6]. Fortunately, our patient's condition responded remarkably well to cryotherapy.…”
“…Treatment of this condition remains discouraging with variable responses to keratolytics, cryotherapy, 5-fluorouracil, imiquimod, calcipotriol, diclofenac, corticosteroids, topical antifungals, and lasers [1,6]. Fortunately, our patient's condition responded remarkably well to cryotherapy.…”
“…The main differential diagnoses are common warts and psoriasis. 2 , 3 In dermoscopy of verruca vulgaris, papillomatosis and dilation of the capillaries of the dermal papillae are observed, and hyperkeratosis may be evidenced according to the clinical presentation of the lesion. 4 In the case of porokeratosis ptychotropica, only hyperkeratosis was observed and the other components of the viral warts were missing.…”
Porokeratosis is a disorder of epidermal keratinization characterized clinically
by a distinctive ridge-like border, and histologically by cornoid lamellae. The
known clinical variants of porokeratosis are: classic porokeratosis of Mibelli,
disseminated superficial (actinic) porokeratosis (DSAP), porokeratosis palmaris
et plantaris disseminata, linear porokeratosis and punctate porokeratosis. In
1995, a seventh form was described as porokeratosis ptychotropica: a verrucous
form resembling psoriasis involving the gluteal cleft presenting on the
histological exam multiple cornoid lamellae. There are very few reports in the
literature of this clinical variant. The present study describes the case of a
healthy male presenting gluteal hyperkeratotic plaques for 22 years. He had been
to several dermatologists, none of them had achieved a definitive diagnosis. We
present a typical clinical presentation and its dermoscopy findings, in addition
to histological examination that confirmed the diagnosis.
“…En inmunocomprometidos puede presentarse en la región anogenital, y pueden ser difícil de diferenciarlas de patología por HPV; su diagnóstico es histológico. 48 La enfermedad de Paget perianal, patología poco frecuente, presenta características clínicas que la hacen difícil de distinguir de lesiones asociadas al HPV por lo que se precisan biopsia y técnicas de inmunohistoquímica para hacerlo. 49 Otra entidad con las que pueden confundirse es la psoriasis invertida perianal (Fig.…”
Dedicamos este relato a todos aquellos que día a día luchan por ser visibilizados: a las mujeres en general y a las cirujanas en particular; a los hispano parlantes, principalmente de lugares que no pertenecen al denominado primer mundo; a los que producen conocimiento en países no hegemónicos; a los que tienen un acceso dificultoso al sistema de salud y, en especial, a los que padecen infecciones sexualmente transmisibles y no encuentran a un profesional integralmente preparado para atenderlos.
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