Genetic diversity of the Polish Hunting Dog population based on pedigree analyses and molecular studies

Goleman, M.; Balicki, I.; Radko, Anna; Jakubczak, Andrzej; Fornal, Agnieszka

doi:10.1016/j.livsci.2019.09.017

Cited by 16 publications

(30 citation statements)

References 14 publications

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“…The number of founders with both unknown parents in the Polish Greyhounds was similar to that calculated in the case of Polish Hunting Dogs (27 and 26, respectively), while a fairly large difference in this number was found in all founders with at least one unknown parent (83 individuals in the Polish Greyhounds and only 31 individuals in Polish Hunting Dogs) [ 21 ]. Considering the number of potential founders (living individuals at reproductive age that have not had offspring), there were only 4 such Polish Greyhound individuals vs. 22 individuals in the group of Polish Hunting Dogs [ 21 ], which indicates the nearly full use of dogs of unknown origin (NN) in breeding. However, the analysis of the use of all founders (with at least one unknown parent) from the beginning of the studbook establishment revealed as many as 45 with no offspring; therefore, the use of the group of founders for breeding purposes was 45.78%.…”

Section: Discussionsupporting

confidence: 66%

“…The average relatedness was estimated to be 17.25% in the Polish Greyhound, while a very low level (1.46%) was reported in the Istrian Shorthaired Hound [ 25 ]. As indicated by the comparison of the Polish breeds of hunting dogs, the participation of the Founder Genome Equivalent in the Polish Greyhounds was 3.61, which was lower than in Polish Hunting Dogs (4.17) [ 21 ] and higher than in Polish Hounds (1.287) [ 22 ]. As shown by Mäki [ 26 ], this value was 2.1 in Nova Scotia Duck Tolling Retrievers and 6.4 in Lancashire Heelers.…”

Section: Discussionmentioning

confidence: 99%

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Pedigree and Molecular Analyses in the Assessment of Genetic Variability of the Polish Greyhound

Goleman

Balicki

Radko

et al. 2021

Animals

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The aim of the study was to assess the genetic variability of the Polish Greyhound population based on pedigree analysis and molecular DNA testing and to determine the degree of relatedness among individuals in the population. Pedigree data of 912 Polish Greyhounds recorded in pedigree books since they were opened for this breed were analyzed. For molecular testing, DNA was obtained from cheek swabs taken from 235 dogs of the tested breed. A panel of 21 markers (Short Tandem Repeat—STR) was used. The mean inbreeding determined for the Polish Greyhound population based on pedigree analyses was low and amounted to 11.8%, but as many as 872 individuals of the 912 dogs in the studied population were inbred. A total of 83 founders (at least one unknown parent) were identified, among which 27 founders had both unknown parents. Full-sibling groups consisted of 130 individuals, with a minimum and maximum litter size of 2 and 16, respectively. The average litter size was 5.969. Gene diversity calculated based on the mean kinship matrix was 0.862 and the population mean kinship was 0.138. The founder genome equivalent based on the mean kinship matrix was 3.61; the founder genome surviving level was 12.34; the mean Ne was estimated at 21.76; and the Ne/N ratio was 0.135. The FIS inbreeding coefficient for 21 STR was negative, and the mean FIS value for all loci had a low negative value (−0.018). These values suggest a low level of inbreeding in the examined breed as well as the avoidance of mating related animals.

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Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Pedigree and Molecular Analyses in the Assessment of Genetic Variability of the Polish Greyhound

Goleman

Balicki

Radko

et al. 2021

Animals

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“…It is genetically well distinguished from other livestock guard dogs from the Western Balkans, Karst Shepherd and Tornjak [25]. We report levels of genetic diversity in YSD which are in the range of those reported by Dimitrijević [2008] and Ceh and Dovc [25], and are comparable and in some cases even higher than those found in numerous dog breeds studied to date by means of nuclear microsatellites [4,[11][12][13][14][15][16][17][18][19][20][21][22][23]. Thus, despite the decline of the YSD population after both 20 th century World Wars, this breed remains genetically highly diverse.…”

Section: Discussionsupporting

confidence: 68%

“…That, along with the historical variations in population sizes, have resulted in the considerable inbreeding and loss of genetic variability in certain purebred dog populations [5][6][7][8], as well as in the increased incidence of inherited diseases [9][10][11]. Although genetic make-up of numerous dog breeds has been studied to date [4,[11][12][13][14][15][16][17][18][19][20][21][22][23], the knowledge regarding genetic structure of non-cosmopolitan dog breeds and local canine populations is still grossly lacking [21,24].…”

Section: Introductionmentioning

confidence: 99%

Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

et al. 2020

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Yugoslavian Shepherd Dog - Sharplanina (YSD) is a livestock guard dog from the Western Balkans present in this region over a long time, but recognized by the Fédération Cynologique Internationale as a distinct breed as late as 1957. However, the information regarding the origin and the size of the breed’s foundation stock is still lacking. In order to contribute towards better understanding of the genetic make-up of the YSD and its foundation stock, we re-analyzed previously generated genetic profiles of 94 registered YSD dogs assessed with nine nuclear microsatellites. Studied individuals comprised 90 unrelated dogs and two pairs of full-sibs, sampled at four sampling sites: three dog shows and at a military training centre for dogs in Serbia. We supported earlier findings on high levels of genetic diversity in YSD (HE=0.728±0.027) and lack of inbreeding, and revealed substructure of the breed because we found two distinct gene pools in the Bayesian clustering analysis, indicated also by the excess of homozygotes (i.e., Wahlund effect) and outcomes of other analyses: linkage disequilibrium tests, Neighbour-Joining tree, principal coordinates and two-dimensional scaling analyses. The two gene pools were almost equally represented at each sampling site. One gene pool was composed of individuals with high genetic integrity, while the other gene pool was characterized with admixed ancestry, developed possibly via hybridization with native breeding stock outside the registry system, other breeds, such as the Caucasian Shepherd, and/or individuals admixed with wolves. Thus, we demonstrate rather complex and diverse ancestry implying a genetically heterogeneous foundation stock of the YSD.

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“…In the previous ten years, the genetic variability of many breeds has been analyzed across countries. Some of them are complex [7][8][9], and some of them are exclusively of a genealogical [10][11][12][13][14][15] or molecular nature [16,17]. However, all of them showed some disconcerting data in at least one studied breed.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Genetic Diversity in the Czech Spotted Dog

Machová

Kranjčevičová

Vostrý

et al. 2020

Animals

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Loss off genetic diversity negatively affects most of the modern dog breeds. However, no breed created strictly for laboratory purposes has been analyzed so far. In this paper, we sought to explore by pedigree analysis exactly such a breed—the Czech Spotted Dog (CSD). The pedigree contained a total of 2010 individuals registered since the second half of the 20th century. Parameters such as the mean average relatedness, coefficient of inbreeding, effective population size, effective number of founders, ancestors and founder genomes and loss of genetic diversity—which was calculated based on the reference population and pedigree completeness—were used to assess genetic variability. Compared to the founding population, the reference population lost 38.2% of its genetic diversity, of which 26% is due to random genetic drift and 12.2% is due to the uneven contribution of the founders. The reference population is highly inbred and related. The average inbreeding coefficient is 36.45%, and the mean average relatedness is 74.83%. The effective population size calculated based on the increase of inbreeding coefficient is 10.28. Thus, the Czech Spotted Dog suffered significant losses of genetic diversity that threaten its future existence.

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Genetic diversity of the Polish Hunting Dog population based on pedigree analyses and molecular studies

Cited by 16 publications

References 14 publications

Pedigree and Molecular Analyses in the Assessment of Genetic Variability of the Polish Greyhound

Pedigree and Molecular Analyses in the Assessment of Genetic Variability of the Polish Greyhound

Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

Analysis of Genetic Diversity in the Czech Spotted Dog

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