GeneralPrinciples

Yanamandra, Niraj; Chandraharan, Edwin

doi:10.1017/cbo9780511842153.002

Cited by 10 publications

(9 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The hormones oestrogen, progesterone, prostacyclins and prostaglandin E2 act as vasodilating factors thereby reducing the systemic vascular resistance. In addition decreases in pressures are also due to arteriovenous shunting in placenta [11]. Our study is in agreement with the findings of studies by Schier RW and Voss A et al, [12,13].…”

Section: Discussionsupporting

confidence: 94%

A Prediction Formula for Double Product in Pregnancy

Teli

Bagali

Ghatanatti

2016

JCDR

View full text Add to dashboard Cite

IntrOductIOnPregnancy is the most important and essential physiological adaptation in the body. Overwhelming changes occur virtually in all the systems of the body, modifications in the cardiovascular system are constituent of the same. Systolic and diastolic blood pressures are found to decrease during second trimester. Cardiac output, heart rate and stroke volume tend to increase during pregnancy, thereby reducing the myocardial oxygen demand [1].Myocardial oxygen consumption is relatively high compared to other organs. High oxygen consumption by the myocardium is required for the contraction and relaxation of cardiac muscle. Hence, the myocardial metabolism and function are closely related [2]. These adaptations during pregnancy are usually well tolerated by healthy women. However, there is a threat to those who are with ischemic heart diseases.Acute Myocardial Infarction (AMI) is rare in women of child bearing age. But increase in risk of AMI has been shown from 3-4 fold [3][4][5][6]. Recent advances in reproduction and child bearing by older women are expected to increase the occurrence of AMI [7].

show abstract

Section: Discussionsupporting

confidence: 94%

A Prediction Formula for Double Product in Pregnancy

Teli

Bagali

Ghatanatti

2016

JCDR

View full text Add to dashboard Cite

show abstract

“…This assumption was affirmed by performing a sensitivity analysis (Figure ). Identical BUP concentration–time profiles were observed in all trimesters in the virtual pregnant women with and without an increase (50%) in GFR .…”

Section: Methodsmentioning

confidence: 71%

Gestational changes in buprenorphine exposure: A physiologically‐based pharmacokinetic analysis

Zhang

Kalluri

Bastian

et al. 2018

Brit J Clinical Pharma

View full text Add to dashboard Cite

show abstract

“…Pregnancy is a period from fertilization to development of one or more offspring, known as a fetus or embryo, in a woman's uterus ( 1 ). It is a natural physiological statement that is accompanied with hormonal and metabolic alterations ( 2 ). During pregnancy, the body undergoes physiologic changes in the cardiovascular, metabolic, renal, respiratory and gastrointestinal systems.…”

Section: Introductionmentioning

confidence: 99%

Biochemical Profiles of Pregnant and Non-pregnant Women Attending at the University of Gondar Hospital, Northwest Ethiopia: A Comparative Cross-sectional Study

Alemu

Abebe

Terefe

et al. 2018

Ethiop J Health Sci

View full text Add to dashboard Cite

BackgroundPregnancy is a natural physiological statement with hormonal and metabolic changes that helps the growth and survival of the fetus. However, biochemical profiles derangement may lead to pregnancy complications. Therefore, there is a need for determining biochemical profiles among pregnant women.MethodsA comparative cross-sectional study was conducted among pregnant and non-pregnant women at the University of Gondar Hospital, from February to April, 2015. Fasting blood sample was collected from 139 pregnant and 139 age matched non-pregnant women using systematic random sampling technique. Interviewer-administered questionnaire was used to collect socio-demographic and clinical data. Fasting blood glucose and lipid profile were measured by A25 Biosytemchemistry analyzer using enzymatic calorimetric methods. Data analysis was done using SPSS version 20. Level of significance between groups was analyzed using independent student t-test and Mann-Whitney U test. A p-value of <0.05 was considered as statistically significant.ResultPregnant women as compared to non-pregnant had significantly increased glucose (96.35±14.45 and 81.12±9.86 mg/dl), total cholesterol (211.9±40.88 and 172.40±29.64 mg/dl) [p<0.05], respectively. It had also significantly high triglycerides (190.81±81.04 and 107.43±45.80 mg/dl) and low-density lipoprotein cholesterol (116.03±37.26 and 86.12±27.29mg/dl) [p<05] in pregnant as compared to non-pregnant women. The level of high-density lipoprotein cholesterol was significantly lower in pregnant women (59.58±14.26) than control (63.63±11.4, P <0.05).ConclusionThere were statistically significant increment in glucose, total cholesterol, triglycerides, low-density lipoprotein cholesterol and decrement in high-density lipoprote in cholesterol levels among pregnant women compared with non-pregnant women. Therefore, pregnant women have to be monitored closely for their biochemical profiles to avoid adverse pregnancy outcomes.

show abstract

GeneralPrinciples

Cited by 10 publications

References 14 publications

A Prediction Formula for Double Product in Pregnancy

A Prediction Formula for Double Product in Pregnancy

Gestational changes in buprenorphine exposure: A physiologically‐based pharmacokinetic analysis

Biochemical Profiles of Pregnant and Non-pregnant Women Attending at the University of Gondar Hospital, Northwest Ethiopia: A Comparative Cross-sectional Study

Contact Info

Product

Resources

About