2016
DOI: 10.1590/s1984-82502016000400004
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Gelatin-based microspheres crosslinked with glutaraldehyde and rutin oriented to cosmetics

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Cited by 32 publications
(20 citation statements)
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References 25 publications
(27 reference statements)
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“…Polymeric and lipid nanoparticles nanoparticles are the most studied nanoformulations for rutin. Then, we categorized the major nanoformulations of rutin as follow: Polymeric nanoparticles, lipid‐based nanoparticles, molecular complexes and the other types of nanoparticles (Graziola et al, 2016; Júlio et al, 2019; Pandey et al, 2018; Ramaswamy et al, 2017; Shahi et al, 2019).…”
Section: Nanotechnology Approaches For Improving Rutin Effectsmentioning
confidence: 99%
“…Polymeric and lipid nanoparticles nanoparticles are the most studied nanoformulations for rutin. Then, we categorized the major nanoformulations of rutin as follow: Polymeric nanoparticles, lipid‐based nanoparticles, molecular complexes and the other types of nanoparticles (Graziola et al, 2016; Júlio et al, 2019; Pandey et al, 2018; Ramaswamy et al, 2017; Shahi et al, 2019).…”
Section: Nanotechnology Approaches For Improving Rutin Effectsmentioning
confidence: 99%
“…Therefore, the applications of the gelatin hydrogel in vivo are limited, due to its poor mechanical properties, rapid degradation rate, and low transition temperatures. To obtain suitable mechanical strength and stable gelatin hydrogel, various chemical crosslinking methods have been used, such as glutaraldehyde [ 14 , 15 ] and diisocyanate [ 16 , 17 ]. However, most of the chemical crosslinkers are toxic, and their use as cell-laden matrices for tissue engineering application is limited.…”
Section: Introductionmentioning
confidence: 99%
“…Considering the use of protein-based bioactives, Graziola and co-workers (2016), observed that gelatin at 5.0% w/w, as an amorphous raw-material, was able to improve the SPF of mineral oil-based dispersions containing 6.0% w/w of benzophenone-3 or 7.5% of ethylhexyl methoxycinnamate, from 2.8 to 4.1 and 6.4 to 8.4, respectively. The critical wavelength (nm) of those dispersions was not affected, being kept below 354.5 nm, even in the UVA filter (benzophenone-3) presence (Graziola et al, 2016). Stiefel and Schwack (2014), identified UV spectra alterations of the octocrylene incubated at 37 °C with bovine serum albumin (BSA) compared to the UVB filter alone.…”
Section: Resultsmentioning
confidence: 99%