Gel test assay for IgG subclass detection by GM typing: Application to hemolytic disease of the newborn

Alie-Daram, S; Fournié, A; Dugoujon, Jean‐Michel

doi:10.1002/(sici)1098-2825(2000)14:1<1::aid-jcla1>3.0.co;2-m

Cited by 1 publication

(2 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GM1, which is a glycosphingolipid having one sialic acid, exhibits binding affinity towards IgG [9-11], and the sialic acid consisting of acetyl and glycerol groups plays an important role in carbohydrate-protein interactions [8,23-25]. The binding affinity between HIgG and MEL-A bearing acetyl and erythritol groups was thus investigated using GM1 as a proper reference.…”

Section: Resultsmentioning

confidence: 99%

“…Some of these glycolipids exhibit a high affinity toward glycoproteins as a result of "multivalent or cluster effect" and thus are focused on as a new affinity ligand for immunoglobulins [7,8]. Gangliosides like GM1 and GD1a are known to bind to immunoglobulins [9-11], while asialo-GM1 and GD3 show a specific binding to IgM and IgG, respectively [8,12]. The possibility of developing these membrane glycolipids into the ligand, however, is far from straightforward due to their limited amounts and heterogeneity [13].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mannosylerythritol lipid, a yeast extracellular glycolipid, shows high binding affinity towards human immunoglobulin G

Nakane

Yanagishita

et al. 2001

BMC Biotechnol

View full text Add to dashboard Cite

Background: There have been many attempts to develop new materials with stability and high affinity towards immunoglobulins. Some of glycolipids such as gangliosides exhibit a high affinity toward immunoglobulins. However, it is considerably difficult to develop these glycolipids into the practical separation ligand due to their limited amounts. We thus focused our attention on the feasible use of "mannosylerythritol lipid A", a yeast glycolipid biosurfactant, as an alternative ligand for immunoglobulins, and undertook the investigation on the binding between mannosylerythritol lipid A (MEL-A) and human immunoglobulin G (HIgG).

show abstract