Gastrointestinal tumour masses due to multiple myeloma: a pathological mimic of malignant lymphoma

Griffiths, Ann; Shepherd, N A; Beddall, Andrew; Williams, Jeremy

doi:10.1046/j.1365-2559.1997.1610866.x

Cited by 22 publications

(22 citation statements)

References 3 publications

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“…1 The disease affects patients with a mean age of 60 years (less than 2% of the cases occur before the age of 40) and typically presents with bone pain, mild anemia, fatigue, weight-loss and an elevated sedimentation rate.…”

Section: Discussionmentioning

confidence: 99%

“…Bleeding and intestinal obstruction may also occur. 1,3,4,5 In the presence of a palpable mass, imaging tests are the first to be performed. Contrasted study may be used, and should be avoided in the presence of a sub occlusive presentation and is contraindicated in patients with intestinal obstruction.…”

Section: Discussionmentioning

confidence: 99%

“…The presence of M protein in peripheral blood helps with diagnostic complementation and may occur in cases of solitary plasmocytomas. 1,6,7 Double-balloon enteroscopy allows endoscopic study and biopsies of the entire small intestine, and permits histological diagnosis throughout. Capsule endoscopy may be used; however, it should be avoided in obstructed patients, and does not have the potential for histological confirmation.…”

Section: Discussionmentioning

confidence: 99%

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Plasmocytoma of the Jejunum: Diagnosis by Double-Balloon Enteroscopy

Safatle‐Ribeiro¹,

Souza²,

Baba³

et al. 2007

Clinics

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Plasmocytoma of the Jejunum: Diagnosis by Double-Balloon Enteroscopy

Safatle‐Ribeiro¹,

Souza²,

Baba³

et al. 2007

Clinics

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“…Die überwiegende Mehrheit wird erst intra-oder postoperativ im Rahmen einer Notfalloperation wegen Obstruktionsileus, Perforation oder Blutung erkannt. Im Ausnahmefall sind die exakte Histologie und das Stadium präoperativ verfügbar, sodass hier die Operationsindikation mit dem Ziel der R0-Resektion, der histopathologischen Stadiensicherung, aber auch der Komplikationsprävention gegeben ist [19,26,27] [26,27,[36][37][38]. Für die primären intestinalen NHL liegen derzeit keine Therapieleitlinien vor.…”

Section: Intestinales Lymphomunclassified

Rolle der Chirurgie im Therapiekonzept der gastrointestinalen Lymphome

Verreet¹,

Schmidt²,

Müller³

et al. 2002

Visc Med

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The Role of Surgery in the Therapy of Gastrointestinal Lymphomas The treatment of primary gastric lymphoma is controversial. The role of surgery has come to be questioned with increasing knowledge of the pathogenesis of gastric lymphoma and with new therapeutic approaches such as eradication of Helicobacter pylori . We review published clinical trials of primary gastric lymphoma, including preliminary results of our own prospective multicenter trial. The results of 7 trials of H. pylori eradication and 12 prospective therapeutic trials are discussed. On basis of’ these data it is concluded that surgery with intention of R0 resection is the treatment of choice in stages EI1–EII1 of lowgrade lymphoma, when H. pylori eradication failed. In high-grade lymphomas it is still unclear whether surgery or its primary combination with radio- or chemotherapy should be preferred. The eradication of H. pylori is a promising therapeutic approach for localized low-grade mucosa- associated lymphoid tissue lymphoma. A randomized trial is needed to clarify whether medical or surgical management of localized gastric lymphoma or a combination of is the best treatment modality. 58% of all surgical interventions of intestinal Non-Hodgkin’s lymphomas are performed in an emergency situation. In 42% of cases, the stage could be determined preoperativly with examination by ultrasonography, endosonography, intestinoscopy, Sellink’s enema, thoracic, abdominal/pelvine computed tomography and bone marrow puncture, and intraoperatively by examination of the regional and juxtaregional lymph nodes and liver biopsy. Crucial for the therapy is in all cases the adequate staging even in emergency situations. Only the special knowledge of the entity of the intestinal non-Hodgkin’s lymphoma can lead to the necessary stageadapted multimodal therapy.

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“…Segmental involvement of the gastrointestinal tract in multiple myeloma has been reported very rarely [1][2][3][4][5][6][7]. The clinical case of a 68-year-old man who had chronic diarrhea and severe weight loss is reported.…”

Section: Introductionmentioning

confidence: 99%