2009
DOI: 10.1007/s00405-009-1176-4
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Gastroesophageal reflux/laryngopharyngeal reflux disease: a critical analysis of the literature

Abstract: Despite the wealth of publications on the topic of gastroesophageal reflux and its variants, there are still many unsettled questions before one accepts the prevalent cult of "reflux disease". This study is summarizing the results of the critical analysis of the literature, 436 articles,during the last 30 years. The golden test to identify the patient group suffering from this rather common phenomenon is still lacking. The claimed extra-esophageal manifestations especially in the larynx are non-specific and ma… Show more

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Cited by 26 publications
(22 citation statements)
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“…Due to some controversies over laryngeal findings of reflux [34] , findings of interarytenoid oedema were not included as pathological findings of the larynx. There were, however, 36 subjects with interarytenoid oedema of whom 28 subjects did not have any organic findings in their vocal folds while 8 had other accompanying vocal fold findings.…”
Section: Phoniatric Findingsmentioning
confidence: 99%
“…Due to some controversies over laryngeal findings of reflux [34] , findings of interarytenoid oedema were not included as pathological findings of the larynx. There were, however, 36 subjects with interarytenoid oedema of whom 28 subjects did not have any organic findings in their vocal folds while 8 had other accompanying vocal fold findings.…”
Section: Phoniatric Findingsmentioning
confidence: 99%
“…A critical analysis of the literature in the field concerning gastro oesophageal reflux disease (GORD) and its extra-oesophageal manifestations shows, lack of an ideal method of registering LPR [4]. Many signs in the larynx attributed to LPR are non-specific and are found in normal subjects without symptoms of posterior laryngitis [4,5].…”
Section: Introductionmentioning
confidence: 99%
“…Patients with non-specific symptoms, and findings of posterior laryngitis are believed to be over-diagnosed as having acid reflux, and consequently an inappropriate use of PPIs are prescribed to patients with findings and symptoms unrelated to reflux [3]. A critical analysis of the literature in the field concerning gastro oesophageal reflux disease (GORD) and its extra-oesophageal manifestations shows, lack of an ideal method of registering LPR [4]. Many signs in the larynx attributed to LPR are non-specific and are found in normal subjects without symptoms of posterior laryngitis [4,5].…”
Section: Introductionmentioning
confidence: 99%
“…The increased number of symptoms in this group of patients may be explained by vocal tract discomfort due to irritation caused by the reflux of stomach contents coming into contact with laryngeal and oropharyngeal tissue (21) . Some symptoms, such as throat clearing, pain and/or the feeling of a lump in the throat, are described in the literature (22)(23)(24) as being consequences of gastroesophageal reflux. These symptoms are directly related to five of the seven questions that make up the physical VoiSS score: "Do you cough or clear your throat?"…”
Section: Discussionmentioning
confidence: 99%