Gastroesophageal reflux disease: Important considerations for the older patients

Chait, Maxwell M

doi:10.4253/wjge.v2.i12.388

Cited by 62 publications

(51 citation statements)

References 51 publications

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“…23 In another study by Chait MM et al, postulated that 20% of the adults with GERD have serious complications. 24 Supporting this finding, our study showed that 24% of the patients had complications (12% esophageal ulcer, 6% Barrett's esophagus and 6% esophageal stricture).…”

Section: Discussionsupporting

confidence: 72%

A study of the symptoms of gastro oesophageal reflux disease and the associated risk factors in a tertiary care centre

2019

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Background: Gastro esophageal reflux disease is the commonest pathologies encountered by gastroenterologist in day to day practice. Longstanding and untreated gastro esophageal reflux disease can lead to many complications including adenocarcinoma. This study was conducted to evaluate the various symptoms and to analyze the lifestyle and dietary factors influencing gastro esophageal reflux disease which can be modified.Methods: Hundred patients with gastro-esophageal reflux disease of age more than 18 years were enrolled in the study. Various patient details including demographic details, lifestyle information and symptomatology data were analyzed and compared with complications.Results: Mean age of gastro esophageal reflux disease patients was 56.09±15.93 years. Gastro esophageal reflux disease is more prevalent in males than females. Gastro esophageal reflux disease is more frequent in BMI <25, greater number of co morbidities and in non-vegetarians. Mean age of gastro esophageal reflux disease with complications was 67±11.53 years and without complications was 52.64±15.57 years. No strong association of smoking, alcohol, spicy foods, fried foods, citrus fruits, heavy meals, tea/coffee, aerated drinks, sleep disturbance and effect on work was identified in gastro esophageal reflux disease.Conclusions: Classical symptoms of gastro esophageal reflux disease were not present in all the patients. Higher age of the patient infers higher risk of complications. Daily episodes of heartburn, regurgitation and retrosternal chest pain implies higher risk of complications. Presence of Helicobacter pylori in gastro esophageal reflux disease patients signify higher risk of complications.

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Section: Discussionsupporting

confidence: 72%

A study of the symptoms of gastro oesophageal reflux disease and the associated risk factors in a tertiary care centre

2019

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“…Supporting this finding, present study showed that 28% of the patients had complications (16% esophageal ulcer, 8% Barrett's esophagus and 4% esophageal stricture) and rest 72% of the patients didn't have complications. 30…”

Section: Discussionmentioning

confidence: 99%

A cross sectional study on clinical profile of endoscopic proven gastroesophageal reflux disease

Anshuman¹,

Kulkarni²

2019

Int Surg J

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Background: Gastroesophageal reflux disease (GERD) is one of the main gastrointestinal diseases. It is due to the abnormal reflux of gastric contents into the esophagus or beyond. It has many symptoms and also many complications.Methods: Authors carried out this study to know the common symptoms, complications of GERD and the endoscopic study results regarding the same. 100 patients attending the surgery department at a tertiary care hospital were included in the study.Results: Mean age of participants was 54.09±14.75 years. Authors divided the 100 patients into two groups, GERD with complications (28 patients) and GERD without complications (72 patients). In the present study, out of 100 GERD patients, 73 patients were males (73%) and 27 patients were females (27%) with male to female ratio of 2.7:1. In this study, among 100 GERD patients, body mass index was <25 in 70 patients (70%) and ≥25 in 30 patients (30%). Heartburn was present in 72% patients, regurgitation in 71%, retrosternal chest pain was seen in 68% patients and dysphagia was seen in 29%. Out of 100 GERD patients, 16 patients (16%) had esophageal ulcers, 8 patients (8%) had Barrett’s esophagus, 4 patients (4%) had esophageal stricture and 72 patients (72%) didn’t have any complications.Conclusions: Age and BMI (both p <0.001) of the patients showed significant statistical difference between two groups. Some other studies also showed similar results with higher complications seen in increasing age and increased frequency of symptoms.

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“…In at least one study, PPI's and H2 blockers were found to be equivalent in terms of symptomatic relief. 25 Other studies suggest greater symptomatic improvement may occur with use of the PPIs 22 . However, the management of GERD with PPIs may not be helpful in all cases.…”

Section: Saliva and Gerdmentioning

confidence: 99%

Salivary stimulation-could it play a role in GERD management?

Burgess¹

2018

JOENTR

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Gastroesophageal reflux disease: Important considerations for the older patients

Cited by 62 publications

References 51 publications

A study of the symptoms of gastro oesophageal reflux disease and the associated risk factors in a tertiary care centre

A study of the symptoms of gastro oesophageal reflux disease and the associated risk factors in a tertiary care centre

A cross sectional study on clinical profile of endoscopic proven gastroesophageal reflux disease

Salivary stimulation-could it play a role in GERD management?

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