A cross sectional study on clinical profile of endoscopic proven gastroesophageal reflux disease

Abstract

Background: Gastroesophageal reflux disease (GERD) is one of the main gastrointestinal diseases. It is due to the abnormal reflux of gastric contents into the esophagus or beyond. It has many symptoms and also many complications.Methods: Authors carried out this study to know the common symptoms, complications of GERD and the endoscopic study results regarding the same. 100 patients attending the surgery department at a tertiary care hospital were included in the study.Results: Mean age of participants was 54.09±14.75 years. Authors divided the 100 patients into two groups, GERD with complications (28 patients) and GERD without complications (72 patients). In the present study, out of 100 GERD patients, 73 patients were males (73%) and 27 patients were females (27%) with male to female ratio of 2.7:1. In this study, among 100 GERD patients, body mass index was <25 in 70 patients (70%) and ≥25 in 30 patients (30%). Heartburn was present in 72% patients, regurgitation in 71%, retrosternal chest pain was seen in 68% patients and dysphagia was seen in 29%. Out of 100 GERD patients, 16 patients (16%) had esophageal ulcers, 8 patients (8%) had Barrett’s esophagus, 4 patients (4%) had esophageal stricture and 72 patients (72%) didn’t have any complications.Conclusions: Age and BMI (both p <0.001) of the patients showed significant statistical difference between two groups. Some other studies also showed similar results with higher complications seen in increasing age and increased frequency of symptoms.