Gastric emptying and secretion in the milk‐fed calf

Abstract

4. Glucose and lactose solutions inhibit abomasal emptying as well as acid production.5. Sodium chloride and sodium bicarbonate of low concentration, near isotonic with blood plasma, stimulate abomasal emptying but the bicarbonate is most effective. Hypertonic solutions of these salts inhibit abomasal emptying.6. Pepsin secretion in the abomasum of the calf is not affected by test meals of glucose, lactose, sodium chloride or sodium bicarbonate.7. These results shows a great similarity between the physiology of the abomasum of the milk-fed calf and the simple stomach. This suggests that the same duodenal receptors, discussed by Hunt & Knox (1968), which control gastric movement in man are also effective in controlling gastric emptying in the milk-fed calf.

Duodenal control of gastric emptying in the milk‐fed calf.

“…Fig. 1 The effect on abomasal emptying of infusing sodium bicarbonate or sodium chloride solutions into the duodenum In all experiments the serial test meal technique elaborated by Hunt (1956) and adapted for the abomasum of the milk-fed calf by Bell & Razig (1973a) was used. Both sodium bicarbonate and sodium chloride solutions of rising concentrations were tested.…”

“…The 'test meal' technique and the use of the abomasal cannula have also been described (Bell & Razig, 1973a). Both single and re-entrant duodenal cannulae were placed as close to the pylorus as was reasonable using a method similar to that described by Markowitz (1954) (Fig.…”

“…Measurement of any change in the volume of the test meal was made by the phenol red marker technique already described (Bell & Razig, 1973a). Diagram of the abomasum and proximal duodenum of the calf to show the disposition of the cannulae.…”

The effect of duodenal infusion on the electromyogram of gastric muscle during activation and inhibition of gastric emptying.

“…The surgical procedures for the fitment of abomasal cannulae have been described by Bell & Razig (1973a), duodenal cannulae by Bell & Mostaghni (1975) and for placement of the electroenterographic electrodes by Grivel & Ruckebusch (1972). The experimental animals were usually prepared when they were 10 days old and experiments commenced 7 days later.…”

A radiological study of gastric (abomasal) emptying in calves before and after vagotomy.

“…Operative procedures followed those previously used by Bell & Razig (1973a). Calves of 14 days of age were fitted with a cannula in the body of the abomasun during halothane anaesthesia.…”