Gambaran stadium dan jenis histopatologi kanker payudara di Subbagian Bedah Onkologi RSUP Sanglah Denpasar tahun 2015-2016

Abstract

Background: Breast cancer is a malignant neoplasm disease where in parekim tissue there is abnormal breast tissue growth that is infiltrative and destructive and can metastatic. The high incidence of breast cancer in Indonesia, is not always followed by determination of clinical staging and histopathology completely, whereas clinical staging and histopathology is needed to determine diagnosis and further management. Knowledge of the staging and histopathology is also an important indicator in determining the prognosis of breast cancer. Methods: This research is a descriptive research with cross sectional approach, the data is obtained from medical record in Sanglah General Hospital Center with research subject of patients diagnosed with breast cancer in 2015-2016 then processed and analyzed with the help of SPSS software. Results: Based on stage, breast cancer patients with EBC (Early Breast Cancer) stage were 30.08% with 2.95% of patients with stage I, 13.39% stage IIA, 13.73% stage IIB. Patients diagnosed with LABC stage (Locally Advance Breast Cancer) were 273 (47.47%) patients with 14.78%, 30.95% and 1.73%, respectively, of stage IIIA, IIIB and IIIC patients. In this study also recorded as many as 129 (22.43%) patients with metastatic breast cancer (stage IV). Based on histopathology, 483 (84%) patients with invasive ductal carcinoma, 61 (10.60%) patients with invasive lobular carcinoma, and 31 (5.40%) patients with other types of carcinoma. Conclusions: Based on the results of this study found that patients diagnosed with breast cancer Sanglah Hospital in year 2015-2016 are 575 patients with the most breast cancer staging is Locally Advanced Breast Cancer (LABC) (Stage IIIA, IIIB, IIIC) with 273 (47.47 %) of patients. The most common type of breast cancer histopathology is invasive ductal carcinoma with 483 (84%) patients

Characteristics and Clinical Description of Breast Cancer Patients in Sanjiwani General Hospital at Gianyar

“…Patients with metastatic breast cancer have a median survival rate of only 22 months after treatment [37] The most common histopathological type was invasive carcinoma of no special type grade 2namely 45 (38.8%), and the second most was Invasive carcinoma of no special type grade 3, namely 44 (37.9%) people. This result is different from the research conducted by Diahpradnya (2018) at Sanglah Hospital Denpasar of the 514 patients with the most invasive ductal carcinoma type, namely 61 people (84.7%) while the results in the study of Satya et al in 2015-2016 found that invasive ductal carcinoma the most, namely 483 (84%) people, invasive lobular carcinoma type as many as 61 people (10.60%) [5,6]. In research, Hartaningsih also found 81.9% with the histopathological classification of invasive ductal carcinoma [38].…”

“…In 2016 of 322 patients, 11.81% had invasive lobular carcinoma histopathology, and 4.65% were different types of carcinoma. [6] According to research by Komang Trisna Aryawan et al in 2018 at Sanglah Hospital Denpasar, the highest number of subtypes was triple negative, with patients aged 41-50 years. [7] From these data, it is necessary to conduct research on breast cancer at the Sanjiwani Hospital, Gianyar, to provide public information, education, and counseling.…”

Health-Related Quality of Life in Postmenopausal Women With Advanced Breast Cancer Receiving Adjuvant Hormone Therapy (Ribociclib and Letrozole)

“…Based on the stage, stage IV is known to have a total of 10 patients (34.5%). This is also found in research (Wangsa et al, 2018): late stages have a proportion of 45-55%; this high rate is due to awareness about breast health and a lack of early detection programs.…”

Clinicopathological Profile Of Her2 Positive (Non-Luminal) Breast Cancer Subtype At Haji Adam Malik General Hospital From 2020-2021

“…Biopsy results can be used for the diagnosis of breast cancer and determining the success of the given therapies. 3 Apart from histopathological examination, there is another classification system based on immunohistochemistry test in which the examination procedure uses antibodies as probes to detect antigens in tissue sections or other forms of cell preparations. Through immunohistochemistry examination, the subtype of breast cancer can be identified.…”