Future Treatments for Onychomycosis

Gupta, Aditya K.; Versteeg, Sarah G.

doi:10.1002/9781119226512.ch20

Cited by 5 publications

(4 citation statements)

References 43 publications

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“…The present study of translation and adaptation is only the first step to test the psychometric properties of this instrument in larger samples of the Portuguese population. The present questionnaire will allow a better understanding of the impact of OM on patients’ QOL, which may facilitate the identification of more effective and personalized care strategies [ 22 , 23 ].…”

Section: Discussionmentioning

confidence: 99%

Translation and Cross-Cultural Adaptation of Quality of Life Scale in Patients with Onychomycosis

Silva-Neves

Rego

Alves

et al. 2021

IJERPH

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(1) Background: Onychomycosis (OM) is a fungal nail infection, considered a risk factor for diabetic foot ulcers. It is associated with changes in quality of life, in terms of pain, self-confidence and self-esteem. The aim was to translate and adapt the OM quality of life questionnaire “OnyCOE-tTM–Quality Of Life Questionnaire Onychomycosis (Nail Fungal Condition)”. (2) Methods: This study followed the guidelines proposed by Beaton et al. (2000), where two English to Portuguese translations were performed and, after an expert consensus, a common version was obtained. This was followed by two back-translations. The expert committee achieved semantic equivalence, idioms and concepts. The pre-test was applied to 49 people. The final version and processed data were sent to the authors. (3) Results: We adapted terms semantically, modified statements syntactically, altering items from interrogative to affirmative. (4) Conclusions: The translated version of the “Quality of life–Onychomycosis” questionnaire suggested that it can be used for further studies to test validity and reliability in this population.

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Section: Discussionmentioning

confidence: 99%

Translation and Cross-Cultural Adaptation of Quality of Life Scale in Patients with Onychomycosis

Silva-Neves

Rego

Alves

et al. 2021

IJERPH

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“…Bei Hautveränderungen der CVIan erster Stelle beim Ulcus cruris venosum -treten ebenfalls signifikant häufiger Nagelveränderungen der Zehennägeln vor allem im Sinne von Onychomykosen auf. 19 Sehr häufig Onychomykoseformen 20 Die bei weitem häufigste Form der Onychomykose ist die distolaterale subunguale Onychomykose (DSO), bei welcher sich der Pilz von der umgebenden Haut ausgehend via Hyponychium an der Unterseite der Nagelplatte von distal nach proximal zur Matrix ausbreitet (Abbildung 1). Dabei verfärbt sich die Nagelplatte gelblich und die subungualen Hyperkeratosen können zu einer Anhebung der Nagelplatte führen.…”

Section: Prädisponierende Faktoren Der Onychomykoseunclassified

S1‐Leitlinie Onychomykose

Nenoff¹,

Reinel²,

Mayser

et al. 2023

J Deutsche Derma Gesell

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ZusammenfassungDie Onychomykose ist eine Pilzinfektion des Nagelorgans und betrifft sowohl Finger‐ als auch Zehennägel. Sie wird in Europa vor allem durch Dermatophyten verursacht. Die Diagnostik erfolgt mittels direktmikroskopischer, kultureller und/oder molekularer Methoden aus Nagelmaterial (Nagelspäne). Eine Lokaltherapie mit antimykotischem Nagellack wird bei leichten oder mäßig ausgeprägten Nagelinfektionen empfohlen. Bei mittelschwerer und schwerer Onychomykose wird empfohlen – falls keine Kontraindikationen bestehen – stets oral (systemisch) zu behandeln. Eine antimykotische Kombinationstherapie – oral und topisch – sollte dabei angestrebt werden. Ziel dieser Aktualisierung der deutschen S1‐Leitlinie ist es, Auswahl und Durchführung von geeigneter Diagnostik und Therapie zu vereinfachen. Die Leitlinie wurde unter Berücksichtigung aktueller internationaler Leitlinien und den Ergebnissen einer Literaturrecherche durch die Experten der Leitlinienkommission erstellt. Die Leitlinienkommission besteht aus Mandatsträgern der Deutschen Dermatologischen Gesellschaft (DDG), des Berufsverbandes der Deutschen Dermatologen (BVDD), der Deutschsprachigen Mykologischen Gesellschaft (DMykG), der Deutschen Gesellschaft für Hygiene und Mikrobiologie (DGHM), der Deutschen Gesellschaft für Kinder‐ und Jugendmedizin e.V. (DGKJ), der Arbeitsgemeinschaft pädiatrische Dermatologie (APD) und der deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI). Methodisch wurde die Leitliniengruppe durch die Division of Evidence‐based Medicine (dEBM) begleitet. Die Leitlinie wurde nach einem umfangreichen internen und externen Review durch die beteiligten Fachgesellschaften freigegeben.

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“…Tight shoes, foot deformities, nail psoriasis, repeated or severe trauma (for example, in sport), artificial fingernails and frequent and excessive transpiration (hyperhidrosis pedis, for example in sport) also promote fungal infection. 20 Distolateral subungual onychomycosis (DSO), in which the fungus spreads from distal to proximal to the matrix, starting from the surrounding skin via hyponychium on the underside of the nail plate, is by far the most frequent form of onychomycosis (Figure 1). The nail plate develops yellowish discoloration and the subungual hyperkeratosis can lead to elevation of the nail plate.…”

Section: Factors Predisposing To Onychomycosismentioning

confidence: 99%

S1 Guideline onychomycosis

Nenoff¹,

Reinel

Mayser

et al. 2023

J Deutsche Derma Gesell

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Summary Onychomycosis is a fungal infection of the fingernails and toenails. In Europe, tinea unguium is mainly caused by dermatophytes. The diagnostic workup comprises microscopic examination, culture and/or molecular testing (nail scrapings). Local treatment with antifungal nail polish is recommended for mild or moderate nail infections. In case of moderate to severe onychomycosis, oral treatment is recommended (in the absence of contraindications). Treatment should consist of topical and systemic agents. The aim of this update of the German S1 guideline is to simplify the selection and implementation of appropriate diagnostics and treatment. The guideline was based on current international guidelines and the results of a literature review conducted by the experts of the guideline committee. This multidisciplinary committee consisted of representatives from the German Society of Dermatology (DDG), the German‐Speaking Mycological Society (DMykG), the Association of German Dermatologists (BVDD), the German Society for Hygiene and Microbiology (DGHM), the German Society of Pediatric and Adolescent Medicine (DGKJ), the Working Group for Pediatric Dermatology (APD) and the German Society for Pediatric Infectious Diseases (DGPI). The Division of Evidence‐based Medicine (dEBM) provided methodological assistance. The guideline was approved by the participating medical societies following a comprehensive internal and external review.

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Future Treatments for Onychomycosis

Cited by 5 publications

References 43 publications

Translation and Cross-Cultural Adaptation of Quality of Life Scale in Patients with Onychomycosis

Translation and Cross-Cultural Adaptation of Quality of Life Scale in Patients with Onychomycosis

S1‐Leitlinie Onychomykose

S1 Guideline onychomycosis

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