Further C32 triterpenoids from Neolitsea pulchella

Abstract

Three further C32 triterpenoids isolated from the stems of Neolitsea pulchella, have been shown to be 3P.24E-dimethoxy-24,25-dimethyl-lanost-9(11 )-ene (I), 24E,-methoxy-24,25-dirnethyl-lanost-9( 1 1 )-en-3-one (11). and 24,24-dimethyI-lanosta-9(11),25-dien-3(3-ol (111). Compounds (I) and (11) are new. Kong THE structures of three new C, , triterpenoids isolated by column chromatography of the light petroleum extract methoxy-24,24-dirnethyl-lanosta-9( 11),25-diene (IV), SOC. (c), 1971, 2826.24,24-dimethyl-lanosta-9( 11) ,254ien-3-one (V), and 3pmethoxy-24,25-dimethyl-lanost-9( 1 l)-en-24<-01 (VI) .l A Of the stems Of Neoldsea $uzchelza were found to be 38-1 W.

Chemical constituents of plants from the genus Neolitsea

“…Chan and Hui isolated three C 32 triterpenes 71-73 by column chromatography of the light petroleum extract [23]. In addition, analysis of a larger quantity of a similar extract led to the discovery of three related minor triterpenes 74-76 [22,23]. Compound 77, a new cycloartane, was reported from N. sericea in 1993, and further investigation of this plant revealed three new lanostanes 78-80, along with a known compound 81 [24,43].…”

“…Investigation of the ethyl acetate-soluble extract of the leaves of N. hiiranensis led to the isolation of hiiranterpenone 70 [3]. Chan and Hui isolated three C 32 triterpenes 71-73 by column chromatography of the light petroleum extract [23]. In addition, analysis of a larger quantity of a similar extract led to the discovery of three related minor triterpenes 74-76 [22,23].…”

Natural neo acids and neo alkanes: Their analogs and derivatives

“…Some neo alkanes (137,(149)(150)(151)(152)(153)(154)(155)(156)(157)(158)(159)(160) have been isolated from plants. In cooked samples of black-salsify (Scorzonera hispanica), a member of the Asteraceae family, were found 114 com-ponents, including two neo alkanes (137 and 155) (171).…”

“…Three triterpenoids, 3β-methoxy-24-methyl-lanost-9(11)en-24-ol (102), 24ξ-methoxy-24,25-dimethyl-lanost-9(11)-en-3-one (103), and 3β,24ξ-dimethoxy-24,25-dimethyllanost-9(11)-ene (104), were isolated from Neolitsea pulchella (Lauraceae, Hong Kong, also known as Neolitsea) (136,137). Two triterpenoids, 24,25-dimethyl-9(11),23-lanostadienol (105) and 24,25-dimethyl-lanosta-9(11),23-dien-3-one (106), were obtained from the stems of Quercus spp.…”