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The development of graphene‐based responsive material has gained tremendous attention in recent decades and has led to search for alternative 2D materials beyond graphene. In recent years, due to their large surface‐to‐volume ratio, atomic thickness, and excellent selectivity of molecular adsorption, 2D materials beyond graphene, including hexagonal boron nitride, transition metal dichalcogenides, black phosphorus, and MXenes, have exhibited great potential in stimuli‐responsiveness. This review explores the five representative stimulus behaviors (temperature, light, gas, electric, and water) of 2D materials beyond graphene and their applications in sensors, detectors, smart devices, photothermal therapy, and actuators. To understand these stimuli‐responsive behaviors in depth, the typical responsive mechanisms are also described. This review summarizes the recent progress in stimuli‐responsive 2D materials beyond graphene and future perspectives to inspire broader and more combined designs using multiple stimuli, and to motivate more exciting developments based on these promising 2D materials beyond graphene.

COVID-19 as an epidemic disease has spread across the planet since December 2019. The somber situation reminds each country to take actions in preventing the spreading of the virus. China as one of the early affected countries has been fighting against the novel coronavirus with the achievements of nearly 80,000 cured confirmed patients. Traditional Chinese medicine (TCM) has made contributions to the treatment of COVID-19 because of its efficacy and comprehensive therapeutic theory. In this commentary, the advantage, etiology and mechanism of TCM therapy were discussed in the aspect of its functions in reducing the harms brought by COVID-19 to human beings.

Staphylococcus aureus is a pathogen that can cause a wide range of infections in humans. Studies have suggested that CRISPR-Cas systems can drive the loss of integrated mobile genetic elements (MGEs) by chromosomal targeting. Here we demonstrate that CRISPR-mediated cleavage contributes to the partial deletion of integrated SCCmec in methicillin-resistant S. aureus (MRSA), which provides a strategy for the treatment of MRSA infections. The spacer within artificial CRISPR arrays should contain more than 25 nucleotides for immunity, and consecutive trinucleotide pairings between a selected target and the 5′ tag of crRNA can block targeting. These findings add to our understanding of the molecular mechanisms of the type III-A CRISPR-Cas system and provide a novel strategy for the exploitation of engineered CRISPR immunity against integrated MGEs in bacteria for clinical and industrial applications.