Furoate Based Functionalised Ionic Liquid: Antimicrobial and Antioxidant Studies

Abstract

A tetraalkyl ammonium cation and furoate anion based functionalised ionic liquid (FIL), N-methyl-N,N,N-trioctylammonium furoate ([MTOA]+[FA]–) has been synthesised and characterised using FT-IR, NMR, and UV spectroscopic techniques. The invitro antimicrobial activity of the synthesised FIL against two types of Gram-positive bacteria, namely Staphylococcus aureus and Enterobacter faecalis as well as Gram-negative bacteria, namely Escherichia coli and Pseudomonas aeruginosa was tested using a well diffusion method. Similarly, an antifungal test was done against Candida albicans. [MTOA]+[FA]– showed significant inhibitory effect against all the organisms tested as compared with the chosen standards. Antibacterial activity against gram-positive bacteria (zone of inhibition: 16 to 30mm) was found to be higher than that of Gram-negative bacteria (zone of inhibition: 11 to 19mm). Moreover, the antioxidant activity of the synthesised FIL from a ferrous ion (Fe2+) chelating assay and its scavenging activity against 1,1-diphenyl-2-picrylhydrazyl, H2O2, and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) free radical using spectrophotometric methods are reported. The FIL, [MTOA]+[FA]– showed a moderate antioxidant activity.

L‐Carnitine‐Based Bio‐Ionic Liquids as Antioxidants

“…The papers published by our group thus far describe antioxidant ILs based on phenolic acids such as caffeic, ellagic, gallic, ferulic, protocatechuic and gentisic acids or antioxidant compounds such as abietic acid, L‐ascorbic acid or 2‐furoic acid [28–35] . Moreover, ILs were used in the production of iongels based on e. g. gelatin or carbon nanotubes and exhibiting antioxidant properties [36–38] .…”

“…[27] The papers published by our group thus far describe antioxidant ILs based on phenolic acids such as caffeic, ellagic, gallic, ferulic, protocatechuic and gentisic acids or antioxidant compounds such as abietic acid, L-ascorbic acid or 2-furoic acid. [28][29][30][31][32][33][34][35] Moreover, ILs were used in the production of iongels based on e. g. gelatin or carbon nanotubes and exhibiting antioxidant properties. [36][37][38] The purpose of this work was to determine the characteristics of bio-based ILs containing only anions derived from naturally occurring L-ascorbic acid and phenolic acids and cations based on L-carnitine.…”