Fungi in mangrove ecosystems and their potential applications

Jia, Shu-Lei; Chi, Zhe; Liu, Guanglei; Huang, Zhong

doi:10.1080/07388551.2020.1789063

Cited by 30 publications

(19 citation statements)

References 72 publications

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“…At present, few antifungal drugs are available on the market, and many of them could not treat drug-resistant fungi. Fungi and bacteria show various interactions in different ecosystems, from cozy existence to depredation [ 73 ]. The first antifungal drug was discovered in a bacterial strain mediator of such interaction, and the bacterial population continues to be the best source of antifungal drugs.…”

Section: Discovery Of Drugs From Cave Ecosystemsmentioning

confidence: 99%

Cave Microbes as a Potential Source of Drugs Development in the Modern Era

et al. 2021

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The world is constantly facing threats, including the emergence of new pathogens and antibiotic resistance among extant pathogens, which is a matter of concern. Therefore, the need for natural and effective sources of drugs is inevitable. The ancient and pristine ecosystems of caves contain a unique microbial world and could provide a possible source of antimicrobial metabolites. The association between humans and caves is as old as human history itself. Historically, cave environments have been used to treat patients with respiratory tract infections, which is referred to as speleotherapy. Today, the pristine environment of caves that comprise a poorly explored microbial world is a potential source of antimicrobial and anticancer drugs. Oligotrophic conditions in caves enhance the competition among microbial communities, and unique antimicrobial agents may be used in this competition. This review suggests that the world needs a novel and effective source of drug discovery. Therefore, being the emerging spot of modern human civilization, caves could play a crucial role in the current medical crisis, and cave microorganisms may have the potential to produce novel antimicrobial and anticancer drugs.

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Section: Discovery Of Drugs From Cave Ecosystemsmentioning

confidence: 99%

Cave Microbes as a Potential Source of Drugs Development in the Modern Era

et al. 2021

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“…Mangroves are important halophyte plants in tropical and subtropical tidal flats such as Guangdong, Guangxi, Fujian, and Hainan, and are of great importance for ecological maintenance, purification, and marine aquaculture [ 46 ]. There are 38 mangrove species in China [ 29 , 47 ].…”

Section: Utilization Of Halophytesmentioning

confidence: 99%

Protection of Halophytes and Their Uses for Cultivation of Saline-Alkali Soil in China

Liu

Wang

2021

Biology

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Over 800 million hectares of arable lands are affected by salinity in the world. In China, saline-alkali soils account for 25% of farmland and are underutilized. One sustainable strategy to make better use of saline land is to plant halophytes, salt-tolerant plants that can survive and complete their life cycle in media containing more than 200 mM NaCl. Halophytes have potential economic value as grain, vegetable, fruit, medicine, animal feed, and biofuel feedstocks, and in greening and coastal protection. Therefore, the cultivation and protection of halophytes is very important. In the past few decades, a lot of work has been done on the protection and utilization of halophytes in saline soil improvement and development worldwide. This article focuses on the distribution of saline-alkali conditions and current measures to protect halophytes, as well as the application of halophytes in the sustainable development of saline-alkali land. This information is helpful for protection and utilization of halophytes in the sustainable development of saline land worldwide.

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“…A mangrove is a unique ecosystem distributed along the coastline of the tropical and subtropical regions, whose specific saline environment is what gives rise to its diverse microbial population [ 1 ]. Additionally, the biodiversity of fungi is more abundant than that of other mangrove microorganisms, which has a fairly good prospect of exploration that causes overwhelming focus [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-Tumor Secondary Metabolites Originating from Fungi in the South China Sea’s Mangrove Ecosystem

Luo

Zhang

et al. 2022

Bioengineering

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A mangrove is a unique ecosystem with abundant resources, in which fungi are an indispensable microbial part. Numerous mangrove fungi-derived secondary metabolites are considerable sources of novel bioactive substances, such as polyketides, terpenoids, alkaloids, peptides, etc., which arouse people’s interest in the search for potential natural anti-tumor drugs. This review includes a total of 44 research publications that described 110 secondary metabolites that were all shown to be anti-tumor from 39 mangrove fungal strains belonging to 18 genera that were acquired from the South China Sea between 2016 and 2022. To identify more potential medications for clinical tumor therapy, their sources, unique structures, and cytotoxicity qualities were compiled. This review could serve as a crucial resource for the research status of mangrove fungal-derived natural products deserving of further development.

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Fungi in mangrove ecosystems and their potential applications

Cited by 30 publications

References 72 publications

Cave Microbes as a Potential Source of Drugs Development in the Modern Era

Cave Microbes as a Potential Source of Drugs Development in the Modern Era

Protection of Halophytes and Their Uses for Cultivation of Saline-Alkali Soil in China

Anti-Tumor Secondary Metabolites Originating from Fungi in the South China Sea’s Mangrove Ecosystem

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