Functional performance status of hematopoietic SCT recipients in the sub-acute phase of recovery

Abstract

This study assessed the functional capacity of sub-acute SCT recipients using validated physical performance tests, including 6-min walk distance, repeated sit-to-stand time and 50-ft walk time, and compared these outcomes with those reported for a heterogeneous oncology population. The medical records of 80 consecutive sub-acute SCT recipients not receiving corticosteroids were retrospectively reviewed for demographic, medical and anthropometric information, and outcomes for these physical performance tests administered at the time of initial physiotherapy evaluation. Measures of central tendency, 95% confidence intervals, unpaired t-tests and correlation coefficients were calculated using a SPSS statistical package. SCT recipients completed the 50-ft walk in 10.66 ± 4.43 s, repeated sit-to-stand trial in 4.16 ± 1.82 s and walked 400.2 m in 6 min. For the timed tests, SCT recipients were approximately twice as fast as a heterogeneous group of oncology patients and walked approximately 50% further in 6 min. No overlap in the 95% confidence intervals for the two groups was observed for any of the tests. These results (1) suggest that reference values describing the functional capacity of a heterogeneous oncology population underestimate the functional capacity of SCT recipients and (2) provide clinically useful reference values for assessing functional capacity of sub-acute SCT recipients referred for physiotherapy.

Impact of oesophagectomy on physical fitness and health-related quality of life in patients with oesophageal cancer

“…The loss of physical fitness was less than expected considering the extent of the surgical intervention. In the 6-min Walk Test, the patients in this study were able to walk approximately 87% of the distance walked by community-dwelling elderly (age, 60-69) (Steffen et al 2002) and about 21% further than the distance walked by haematopoietic cancer patients (average age, 54 years) during the posttransplant recovery period (Morris et al 2010). Perioperative physiotherapy may have helped maintain their physical fitness.…”

“…) and about 21% further than the distance walked by haematopoietic cancer patients (average age, 54 years) during the post‐transplant recovery period (Morris et al . ). Peri‐operative physiotherapy may have helped maintain their physical fitness.…”

“…; Morris et al . ). Thus, 6‐min walking distance may be one of the good indicators of HRQOL shortly after oesophagectomy.…”

“…The results of our multiple regression analysis showed that change in 6-min walking distance was the variable most closely associated with change in PF score. The distance one can walk in a given period of time is an important index of one's quality of life and helps to define the ability of a patient to undertake or participate in day-to-day activities (Guyatt et al 1985;Redelmeier et al 1997;Morris et al 2010). Thus, 6-min walking distance may be one of the good indicators of HRQOL shortly after oesophagectomy.…”

Impact of HSCT Conditioning and Glucocorticoid Dose on Exercise Adherence and Response

“…Moreover, in another publication the authors report on adherence data in a comparable patient group of allo-HSCT patients without GC treatment. In this group, the adherence was lower, but no exact numbers were reported (21,22). Regarding training response, the comparison of both studies by Morris et al indicated a slightly better response in non-GC treated patients, however, no direct comparison between studies was performed (22).…”