“…Patients with darker phototypes also more commonly have longitudinal melanonychia resulting from nail trauma or inflammation. Nail biting, 57 friction, 58 inflammatory diseases such as psoriasis and systemic lupus erythematosus, 59 hydroxyurea treatment, 60 psoralen plus ultraviolet A, 61 pregnancy, 62 and drugs (among which chemotherapeutics are most common) 63 have all been associated with melanotic pigmentation of the nail resulting from stimulation of melanocytes (Fig 6). In drug-induced melanonychia, pigmentation will usually fade over months to years after withdrawal of the offending agent.…”