Diagnosis and management of nail pigmentations

Braun, Ralph P.; Baran, Robert; Gal, Frédérique Anne Le; Dalle, S.; Ronger, Sandra; Pandolfi, Roberta; Gaide, Olivier; French, Lars E.; Laugier, P; Saurat, J.‐H.; Marghoob, Ashfaq A.; Thomas, Luc

doi:10.1016/j.jaad.2006.12.021

Cited by 265 publications

(266 citation statements)

References 44 publications

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“…Dermoscopy of fungal melanonychia reveals a brown or black irregular band associated with thick subungual hyperkeratosis with yellow and brown scales (Fig. 23) [40,41]. Additional dermoscopic features of fungal melanonychia include: multicolored pigmentation (yellow, brown, gray, black, or red), matt black pigmentation (lines, disrupted black linear pigmentation, or homogeneous areas), black pigment aggregates (seen as coarse granules and/or pigment clumps), and pigmentation that is wider at the distal than at the proximal edge, called the “black reverse triangle” [40,42].…”

Section: Alterations Of the Nail Platementioning

confidence: 99%

Dermoscopy in the Evaluation of Nail Disorders

Alessandrini

Starace

Piraccini³

2017

Skin Appendage Disord

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Nail dermoscopy was initially used only in the assessment of nail pigmentation, but now it is widely utilized for the evaluation of many nail disorders. In daily practice, dermoscopy may confirm clinical diagnoses and guides in the management of nail diseases and treatments, permitting a better visualization of symptoms. Dry dermoscopy is required for evaluation of the nail plate surface, while gel as an interface is necessary for assessment of nail pigmentation and onycholysis, as well as for the evaluation of the distal nail margin. In this review, we describe the dermoscopic features of the most important nail disorders, looking at the different areas of the nail. Dermatoscopic changes that usually accompany specific nail diseases are also reviewed.

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Section: Alterations Of the Nail Platementioning

confidence: 99%

Dermoscopy in the Evaluation of Nail Disorders

Alessandrini

Starace

Piraccini³

2017

Skin Appendage Disord

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“…A regular pattern of pigments indicates the existence of a benign lesion such as a nevus. Irregular pattern of brown pigments with no parallelism and uneven spacing and thickness is suggestive of a malignant melanoma [10] . The use of dermoscopy for the diagnosis of hair and scalp illnesses has also been recently described.…”

Section: Received: 18mentioning

confidence: 99%

Dermoscopy: Where are we?

Aghaei

2016

J Surg Dermatol

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“…Additionally, other factors may contribute to the difficulty of lesion classification, such as subungual formations where optical attenuation and scattering are caused by the compacted keratin structure of the nail. 1 The clinical danger of misclassification arises when a melanoma or a precancerous pigmented lesion is identified as a vascular lesion. To improve diagnosis, we developed a photoacoustic probe used previously in skin measurements [2][3][4] and used classical and Bayesian statistical classification methods for differentiating between pigmented and vascular lesions.…”

Section: Introductionmentioning

confidence: 99%

Photoacoustic discrimination of vascular and pigmented lesions using classical and Bayesian methods

et al. 2010

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Abstract. Discrimination of pigmented and vascular lesions in skin can be difficult due to factors such as size, subungual location, and the nature of lesions containing both melanin and vascularity. Misdiagnosis may lead to precancerous or cancerous lesions not receiving proper medical care. To aid in the rapid and accurate diagnosis of such pathologies, we develop a photoacoustic system to determine the nature of skin lesions in vivo. By irradiating skin with two laser wavelengths, 422 and 530 nm, we induce photoacoustic responses, and the relative response at these two wavelengths indicates whether the lesion is pigmented or vascular. This response is due to the distinct absorption spectrum of melanin and hemoglobin. In particular, pigmented lesions have ratios of photoacoustic amplitudes of approximately 1.4 to 1 at the two wavelengths, while vascular lesions have ratios of about 4.0 to 1. Furthermore, we consider two statistical methods for conducting classification of lesions: standard multivariate analysis classification techniques and a Bayesian-model-based approach. We study 15 human subjects with eight vascular and seven pigmented lesions. Using the classical method, we achieve a perfect classification rate, while the Bayesian approach has an error rate of 20%. © 2010Society of Photo-Optical Instrumentation Engineers.

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Diagnosis and management of nail pigmentations

Cited by 265 publications

References 44 publications

Dermoscopy in the Evaluation of Nail Disorders

Dermoscopy in the Evaluation of Nail Disorders

Dermoscopy: Where are we?

Photoacoustic discrimination of vascular and pigmented lesions using classical and Bayesian methods

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