Functional gastrointestinal disorders in 35 447 adults and their association with body mass index

Abstract

SUMMARY BackgroundFunctional gastrointestinal disorders' (FGIDs) associations with body mass index (BMI) have not been thoroughly investigated in the general population.

Prevalence of Irritable Bowel Syndrome in Singapore and Its Association with Dietary, Lifestyle, and Environmental Factors

“…There were mixed results regarding the association of IBS and obesity. There were studies that found higher IBS prevalence with increased BMI, 49,50 and waist-circumference and visceral adipose tissue. 51 Other authors cautioned regarding selection of study patients and need of a standardized assessment of obesity.…”

Visceral adiposity is associated with an increased risk of functional dyspepsia

“…Le Pluart et al 15 found that IBS and functional constipation frequently coexist in subjects suffering from FD. Our result was consistent with this finding.…”

“…12 A recent large scale study showed that high BMI had a significant association with increased risk of FD in females. 15 Abdominal adipose tissue consists of two functionally and anatomically distinct types of fat, visceral, and subcutaneous adipose tissue. Visceral adipose tissue not only has metabolic effects, 16 but may also increase intra-abdominal pressure.…”

Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source

“…The present study underlines the importance of the enrollment source to define the association between BMI and FGIDs. In fact, independently of the country of origin, previous studies associated BMI and organic or functional digestive disorders in cohort patients from different types of enrollment: functional disease recruitment [28], weight loss programs [29], bariatric surgery [20], endoscopic evaluation [27,30], or epidemiological studies [31,32]. In addition, some studies could include control groups [33] but did not separate obese patients according to their BMI [34].…”