Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source

Bouchoucha, Michel; Fysekidis, Marinos; Julia, Chantal; Airinei, Gheorghe; Catheline, Jean-Marc; Reach, Gérard; Bénamouzig, Robert

doi:10.1007/s11695-015-1679-6

Cited by 24 publications

(19 citation statements)

References 37 publications

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“…These findings could in part explain the differences between the study centres. Differences in prevalence rates of functional gastrointestinal disorders in patients recruited from different types of secondary clinics (gastroenterological or obesity clinics) have recently been highlighted by Bouchoucha et al [11] The current study shows that large differences also exist between clinics of the same type (two obesity clinics).…”

Section: Discussionsupporting

confidence: 49%

Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study

et al. 2017

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BackgroundIrritable bowel syndrome has been reported as more common in patients with morbid obesity than in the general population. The reason for this association is unknown. The aims of this study were to study the prevalence of irritable bowel syndrome and other functional bowel disorders in patients with morbid obesity, and to search for predictors of irritable bowel syndrome.MethodsPatients opting for bariatric surgery at two obesity centers in South-Eastern Norway were included. Functional bowel disorders were diagnosed according to the Rome III criteria. Predictors were evaluated in a multivariable logistic regression analysis with irritable bowel syndrome as the dependent variable.ResultsA total of 350 (58%) out of 603 consecutive patients were included. The prevalence rates of irritable bowel syndrome at the two centers were 17/211 (8%) and 37/139 (27%) respectively. High low-density lipoprotein (OR 2.10; 95% CI 1.34–3.29), self-reported psychiatric disorders (OR 2.39; 95% CI 1.12–5.08) and center (OR 5.22; 95% CI 2.48–10.99) were independent predictors of irritable bowel syndrome.ConclusionsAt one of the two obesity centers, the prevalence of irritable bowel syndrome was threefold higher than in the general population in the same region. The high prevalence appears to be related to dietary differences or altered absorption or metabolism of fat. Attention to irritable bowel syndrome is important in the care of patients with morbid obesity.

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Section: Discussionsupporting

confidence: 49%

Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study

et al. 2017

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“…51 Other authors cautioned regarding selection of study patients and need of a standardized assessment of obesity. 52,53 Larger sample sizes may be needed to elucidate whether there was an association between BMI and IBS. Secondly, a better and more detailed dietary questionnaire with a recorded temporal relationship with symptoms should be utilised in future studies to investigate the effect of diet on IBS.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Irritable Bowel Syndrome in Singapore and Its Association with Dietary, Lifestyle, and Environmental Factors

Siah

Wong

Chan

et al. 2016

J Neurogastroenterol Motil

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Background/AimsThe prevalence of irritable bowel syndrome (IBS) has risen considerably over the past decade in Singapore. We aim to explore the contribution of changes in diet, lifestyle and habits that may contribute to the increased prevalence and development of IBS. MethodsThis is a survey-based cross-sectional population study aimed to gather demographic, socio-economical, lifestyle, dietary, antibiotic usage and other related information. Subjects were adult male or female Singaporeans aged 21 years or above. Association of the factors gathered with the presence or absence of IBS (by Rome III criteria) was assessed using chi-square or Fisher's exact test. Variables with a level of statistical significance of 0.1 or less in the univariate analysis were entered into a stepwise logistic regression model. ResultsA total of 297 subjects participated in the study (female 60.3%). Overall, 20.9% subjects fulfilled the Rome III IBS criteria. Univariate analysis showed that IBS was associated with pet ownership, antibiotic usage, late dinner, (> 9 PM) and consumption of Western meals, coffee, and bread. The multivariate logistic regression analyses showed that IBS was independently associated with being a pet owner (P = 0.008; OR, 2.5; 95% CI, 1.278-5.037). ConclusionsThe prevalence of IBS was 20.9% using the Rome III criteria in our study. The association between IBS and pet ownership will need further investigation. (J Neurogastroenterol Motil 2016;22:670-676)

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“…Fiber has long been recommended for the management of various gastrointestinal (GI) ailments, such as constipation or diarrhea; its mechanism of action is well described elsewhere . In contrast, for many years, dietary fat has been studied in non‐GI diseases, but only recently, the impact of FAs on GI function has become an attractive area of study to combat various GI‐related disorders .…”

Section: Introductionmentioning

confidence: 99%

Changes in the diet composition of fatty acids and fiber affect the lower gastrointestinal motility but have no impact on cardiovascular parameters: In vivo and in vitro studies

Mosińska

Martín‐Ruíz

González

et al. 2019

Neurogastroenterology Motil

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Background Food and diet are central issues for proper functioning of the cardiovascular (CV) system and gastrointestinal (GI) tract. We hypothesize that different types of dietary FAs affect CV parameters as well as GI motor function and visceral sensitivity. Methods Male Wistar rats were fed with control diet (CTRL), diet supplemented with 7% soybean oil (SOY), SOY + 3.5% virgin coconut oil (COCO), and SOY + 3.5% evening primrose oil (EP) for 4 weeks. The content of insoluble fiber in CTRL was higher than in SOY, COCO, or EP. Body weight gain and food/water intake were measured. At day 28, biometric, biochemical, CV parameters, GI motor function (X‐ray and colon bead expulsion test), and visceral sensitivity were evaluated. Changes in propulsive colonic activity were determined in vitro. The colon and adipose tissue were histologically studied; the number of mast cells (MCs) in the colon was calculated. Results SOY, COCO, and EP had increased body weight gain but decreased food intake vs CTRL. Water consumption, biometric, biochemical, and CV parameters were comparable between groups. SOY increased the sensitivity to colonic distention. All groups maintained regular propulsive neurogenic contractions; EP delayed colonic motility (P < 0.01). SOY, COCO, and EP displayed decreased size of the cecum, lower number and size of fecal pellets, and higher infiltration of MCs to the colon (P < 0.001). Conclusions and Inferences Dietary FAs supplementation and lower intake of insoluble fiber can induce changes in the motility of the lower GI tract, in vivo and in vitro, but CV function and visceral sensitivity are not generally affected.

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Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source

Abstract: This study has shown that the recruitment source accounted for marked and specific differences in the prevalence of functional gastrointestinal disorders in obesity and morbid obesity. Symptoms with similar prevalence in all groups should be systematically detected in all patients.

Cited by 24 publications

References 37 publications

Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study

Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study

Prevalence of Irritable Bowel Syndrome in Singapore and Its Association with Dietary, Lifestyle, and Environmental Factors

Changes in the diet composition of fatty acids and fiber affect the lower gastrointestinal motility but have no impact on cardiovascular parameters: In vivo and in vitro studies

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