Prevalence of Irritable Bowel Syndrome in Singapore and Its Association with Dietary, Lifestyle, and Environmental Factors

Abstract

Background/AimsThe prevalence of irritable bowel syndrome (IBS) has risen considerably over the past decade in Singapore. We aim to explore the contribution of changes in diet, lifestyle and habits that may contribute to the increased prevalence and development of IBS. MethodsThis is a survey-based cross-sectional population study aimed to gather demographic, socio-economical, lifestyle, dietary, antibiotic usage and other related information. Subjects were adult male or female Singaporeans aged 21 years or above. Association of the factors gathered with the presence or absence of IBS (by Rome III criteria) was assessed using chi-square or Fisher's exact test. Variables with a level of statistical significance of 0.1 or less in the univariate analysis were entered into a stepwise logistic regression model. ResultsA total of 297 subjects participated in the study (female 60.3%). Overall, 20.9% subjects fulfilled the Rome III IBS criteria. Univariate analysis showed that IBS was associated with pet ownership, antibiotic usage, late dinner, (> 9 PM) and consumption of Western meals, coffee, and bread. The multivariate logistic regression analyses showed that IBS was independently associated with being a pet owner (P = 0.008; OR, 2.5; 95% CI, 1.278-5.037). ConclusionsThe prevalence of IBS was 20.9% using the Rome III criteria in our study. The association between IBS and pet ownership will need further investigation. (J Neurogastroenterol Motil 2016;22:670-676)

The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments

“…[1][2][3][4] It is a common gut disorder with a prevalence of 9-23% 5 which varies amongst different geographical regions and countries, with a higher prevalence in Western Europe and North America compared with other parts of the world which could be explained by a relationship between western lifestyle and gut health. 6,7 Abdominal pain is a prevalent disorder within a healthy population; however, severe and recurrent pain sensation is observed frequently in IBS patients. Such painful sensation released from the gut is considered as the main cause of medical consultation in patients with IBS.…”

E‐Poster presentations – A3) small intestine

“…Conclusion: From the endoscopic findings of BAE, differential diagnosis of small intestinal malignant tumors could be speculated. Affiliation: Departments of [1]Gastroenterology and Hepatology, [2] Pathology, Singapore General Hospital, Singapore…”

“…Discussion: About 80% GIST have tumor recurrence after radical operation (1). Most GISTs recur during the first 5 years and few recur after the first 10 years (2). There are no published data to indicate the optimal surveillance policy.…”

“…# P-0180 Reduced interstitial cells of Cajal density and increased intraepithelial lymphocytes are associated with development of small intestinal bacterial overgrowth in post-infectious IBS mouse model Authors: BINRUI CHEN [1]; SHUWEN ZHU [1]; LIJUN DU [1]; HUIQIN HE [1]; JOHN J KIM [1,2]; NING DAI [1] Affiliations: [1]Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Zhejiang, China; and [2]Division of Gastroenterology, Loma Linda University Medical Center, Loma Linda, USA Background: Intestinal dysmotility and immune activation are likely involved in the pathogenesis of small intestinal bacteria overgrowth (SIBO) in irritable bowel syndrome (IBS). We aimed to investigate the role of interstitial cells of Cajal (ICC) and intestinal inflammation in the development of SIBO using a post-infectious IBS (PI-IBS) mouse model.…”

Critical Appraisal of “Association between Diet and Lifestyle Habits and Irritable Bowel Syndrome: A Case-Control Study”

“…Moreover, few studies considered both diet and lifestyle factors as potential mechanisms for the onset of irritable bowel syndrome (IBS) 1. Since the publication of this study, additional research has been completed in this area, which, in part, contradicts the findings of this study 2. The authors aimed to determine an association between diet and lifestyle habits and IBS using a population-based, case-control design.…”