Frontal Assessment Battery in Early Cognitive Impairment: Psychometric Property and Factor Structure

Goh, Wen Yang; Chan, D.; Ali, Noorhazlina; Chew, Aik Phon; Chuo, A.; Chan, Mark; Lim, Wee Shiong

doi:10.1007/s12603-019-1248-0

Cited by 13 publications

(15 citation statements)

References 34 publications

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“…Notably, our results showed a strong association with the cognitive control rather than the behavioural control domain in the Chinese FAB. The conceptualization and mental flexibility items within the cognitive control domain showed discriminative ability to discern between normal and MCI groups ( 18 ), thereby supporting their utility to detect early impairment in executive function amongst relatively robust older adults with social frailty.…”

Section: Discussionmentioning

confidence: 88%

“…Executive functioning plays an important role in enabling higher-level functions such as planning, making decisions and sourcing for new information, thus maintaining independence in daily life ( 16 , 39 ). Earlier studies in healthy community-dwelling populations have reported that the inability to plan is one of the first signs of cognitive decline ( 18 ). Coupled with social frailty, these individuals will have increasing difficulty in maintaining their independence, leading to eventual disability ( 7 , 11 , 40 ).…”

Section: Discussionmentioning

confidence: 99%

“…Cognitive function was assessed with the CMMSE and the locally validated Chinese FAB ( 17 , 18 , 21 ). The CMMSE consists of 28 questions that assesses six specific cognitive function domains: orientation to time, orientation to place, registration, attention and calculation, recall and language and praxis ( 23 ).…”

Section: Methodsmentioning

confidence: 99%

“…The first domain of cognitive control measures conceptualization, mental flexibility, and motor programming. The second domain of behavioural control measures sensitivity to interference, mental flexibility, and environmental autonomy ( 18 , 19 ). Impairment in executive functioning was determined by education-adjusted cut-offs (Chinese FAB score ≤13 for ≤6 years education, and ≤14 for >6 years education) ( 18 ).…”

Section: Methodsmentioning

confidence: 99%

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Social Frailty and Executive Function: Association with Geriatric Syndromes, Life Space and Quality of Life in Healthy Community-Dwelling Older Adults

et al. 2021

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Background: Despite emerging evidence about the association between social frailty and cognitive impairment, little is known about the role of executive function in this interplay, and whether the co-existence of social frailty and cognitive impairment predisposes to adverse health outcomes in healthy community-dwelling older adults. Objectives: We aim to examine independent associations between social frailty with the MMSE and FAB, and to determine if having both social frailty and cognitive impairment is associated with worse health outcomes than either or neither condition. Methods: We studied 229 cognitively intact and functionally independent community-dwelling older adults (mean age= 67.2±7.43). Outcome measures comprise physical activity; physical performance and frailty; geriatric syndromes; life space and quality of life. We compared Chinese Mini Mental State Examination (CMMSE) and Chinese Frontal Assessment Battery (FAB) scores across the socially non-frail, socially pre-frail and socially frail. Participants were further recategorized into three subgroups (neither, either or both) based on presence of social frailty and cognitive impairment. Cognitive impairment was defined as a score below the educational adjusted cut-offs in either CMMSE or FAB. We performed logistic regression adjusted for significant covariates and mood to examine association with outcomes across the three subgroups. Results: Compared with CMMSE, Chinese FAB scores significantly decreased across the social frailty spectrum (p<0.001), suggesting strong association between executive function with social frailty. We derived three subgroups relative to relationship with socially frailty and executive dysfunction: (i) Neither, N=140(61.1%), (ii) Either, N=79(34.5%), and (iii) Both, N=10(4.4%). Compared with neither or either subgroups, having both social frailty and executive dysfunction was associated with anorexia (OR=4.79, 95% CI= 1.04-22.02), near falls and falls (OR= 5.23, 95% CI= 1.10-24.90), lower life-space mobility (odds ratio, OR=9.80, 95% CI=2.07-46.31) and poorer quality of life (OR= 13.2, 95% CI= 2.38-73.4). Conclusion: Our results explicated the association of executive dysfunction with social frailty, and their synergistic relationship independent of mood with geriatric syndromes, decreased life space and poorer quality of life. In light of the current COVID-19 pandemic, the association between social frailty and executive dysfunction merits further study as a possible target for early intervention in relatively healthy older adults.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Social Frailty and Executive Function: Association with Geriatric Syndromes, Life Space and Quality of Life in Healthy Community-Dwelling Older Adults

et al. 2021

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“…The ST-I is used as a measure of processing speed, and the ST-II is used as a measure of selective attention and inhibition. The frontal assessment battery (FAB) is a short bedside screening instrument that evaluates six domains of frontal lobe function, namely, conceptualization [ 18 ]. The Montreal Cognitive Assessment Scale (MoCA) is a rapid assessment scale that covers cognitive domains such as executive function, language, orientation, calculation, conceptual thinking, memory, visuospatial perception, attention, and concentration [ 19 ].…”

Section: Methodsmentioning

confidence: 99%

The Feasibility and Positive Effects of Wuqinxi Exercise on the Cognitive and Motor Functions of Patients with Parkinson’s Disease: A Pilot Study

Shen

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Introduction. Parkinson’s disease (PD) is a chronic degenerative disease of the central nervous system common in middle-aged and elderly people, which has a serious impact on patients’ cognitive and motor functions. Exercise can improve the nonmotor symptoms of PD patients, but the optimal type of exercise for the cognitive function of patients is unclear. Therefore, the purpose of this study is the impact of 12 weeks of Wuqinxi exercise on the cognitive and motor function in PD patients. Methods. Thirty PD patients participated in the study and were randomly assigned to two groups: Wuqinxi group (n = 15) or stretching group (n = 15). All the participants performed a 12-week exercise program twice a week, 90 min/session. The assessments were conducted before and after exercise intervention, included cognitive function (frontal assessment battery (FAB); Stroop test I and II), motor functions (Unified Parkinson’s Disease Rating Scale Part III (UPDRS-III); timed up and go (TUG)). Results. We found the FAB and Stroop I scores were significantly higher in the Wuqinxi group than in the stretching group. Participants in the Wuqinxi group significantly improved their UPDRS-III (17.73 ± 9.88) and TUG (10.50 ± 1.79) score after 12 weeks of training intervention. Conclusion. The results show that the use of Wuqinxi for rehabilitation therapy for cognition is feasible, widely accepted, and effective in patients with Parkinson’s disease. This study provides preliminary evidence for further large-scale and controlled studies.

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The Frontal Assessment Battery 20 years later: normative data for a shortened version (FAB15)

et al. 2021

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Frontal Assessment Battery in Early Cognitive Impairment: Psychometric Property and Factor Structure

Cited by 13 publications

References 34 publications

Social Frailty and Executive Function: Association with Geriatric Syndromes, Life Space and Quality of Life in Healthy Community-Dwelling Older Adults

Social Frailty and Executive Function: Association with Geriatric Syndromes, Life Space and Quality of Life in Healthy Community-Dwelling Older Adults

The Feasibility and Positive Effects of Wuqinxi Exercise on the Cognitive and Motor Functions of Patients with Parkinson’s Disease: A Pilot Study

The Frontal Assessment Battery 20 years later: normative data for a shortened version (FAB15)

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