Frequency of Dyslipidemia in Ischemic Stroke Patients Presented to Tertiary Care Hospital of Lahore

Jaffar, Murtaza; Rafique, Adil; Khalid, Sidra; Waheed, Shahid

doi:10.53350/pjmhs2115103417

Cited by 4 publications

(4 citation statements)

References 21 publications

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“…In various geographical regions and among diverse ethnic groups, the age at which women become mothers is consistently identified as the primary risk factor associated with hydatidiform mole. 22 A number of studies have proposed that molar pregnancy is strongly associated with specific factors. These factors include nulliparity (having never given birth), lower socioeconomic status, and deficiencies in essential nutrients such as protein, folic acid, and carotene.…”

Section: Resultsmentioning

confidence: 99%

Hydatidiform Mole Types and Age Demographics in Sindh Province, Pakistan

Kainat,

Khan,

Kumar

et al. 2023

PJMHS

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Hydatidiform mole can be classified as partial and complete depending on the clinical and histopathological features. There is regional variation in incidence of hydatidiform mole with more cases seen in Asia, Africa and other developing countries. This cross-sectional descriptive study was done at the department of histopathology in Diagnostic and research laboratory Hyderabad Sindh. A total of 261 cases were added in the study including 251 cases of suction and evacuation and 10 cases of hysterectomy. The mean age was 27.16±6.66 with age range of 17-60 years. In our study out of 260 samples, 155(59.6%) were of complete mole while 105(40.4%) were of partial mole. The incidence of mole was highest in the age group 26-30 years. The prevalence of hydatidiform mole was notably higher in comparison to numerous other studies. In conclusion, it is recommended that all abortion specimens undergo evaluation to prevent misdiagnosis of gestational trophoblastic disease and to ensure appropriate treatment and follow-up, thereby minimizing the risk of complications. Keywords: Hydatidiform mole. Complete mole. Partial mole. Molar pregnancy.

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Section: Resultsmentioning

confidence: 99%

Hydatidiform Mole Types and Age Demographics in Sindh Province, Pakistan

Kainat,

Khan,

Kumar

et al. 2023

PJMHS

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“…Also, dyslipidemia is more common in older age patients >65 years (63.2%) 28 . Consistent with these outcomes, we also found that the mean age of the patients with dyslipidemia was significantly higher than those without.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of males and females was 79% and 21%, respectively, as reported by a local study. Furthermore, they found that the prevalence of dyslipidemia in men and women was 68.4% and 43.7%, respectively 28 .…”

Section: Discussionmentioning

confidence: 99%

Frequency of Dyslipidemia in Ischemic Strokes Involving Different Regions of Brain

Ghafoor¹,

Ali²,

Ashraf³

et al. 2023

PJMHS

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Background: Most strokes are ischemic; the type of artery involved can affect the prognosis and clinical symptoms. The risk factors for stroke include high blood pressure, diabetes, smoking, and elevated cholesterol. It has been demonstrated that lipid profile levels and the prognosis of stroke are related. Aim: To determine the frequency of dyslipidemia in ischemic stroke patients based on the location of the infarct. Study design: Cross-sectional study Place and duration of study: Department of Medicine, Fauji Foundation Hospital Rawalpindi from 10 August to 10 January 2022. Methods: Four hundred patients with MRI-proven ischemic stroke were enrolled. The blood samples were obtained, and a lipid profile was used to determine the lipid abnormalities (dyslipidemia). Results: Middle cerebral artery involvement was the most frequently observed among the enrolled ischemic stroke patients, i.e., 54.8%. The overall frequency of dyslipidemia was 92.3%; hypercholesterolemia, hypertriglyceridemia, high LDL, and low HDL was present in 47.8%, 50.8%, 33.8%, and 93.8%, respectively. All patients with middle cerebral artery involvement had low HDL levels, 34.25% had high LDL levels, 41.10% had high triglyceride levels, and 54.79% had high cholesterol levels. A significant effect of age, gender, recurrent stroke, and location of infarct was observed on the frequency of dyslipidemia. Conclusion: The frequency of dyslipidemia in ischemic stroke patients in Pakistan is relatively high. This emphasized how important it is to reduce these population-wide modifiable risk factors. Keywords: Stroke, Dyslipidemia, Ischemic stroke, Lipid profile

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“…Frequency of hyperlipidemia in patients presenting with ischemic stroke was 37.1% in another study conducted in Multan on 178 patients. 7 Hyperlipidemia is an important risk factor for occurrence of stroke; our main aim is to assess the prevalence of hyperlipidemia in tertiary care hospitals in Karachi as many studies have been done in Pakistan but mostly level of low density lipoproteins or triglyceride levels have been the main point of concern however in our study we have studied the whole lipid profile and also looked into the levels of high density lipoproteins which act as cardio protective as well as a protective agent for stroke. There is a dearth of reliable figures for the prevalence of hyperlipidemia in Pakistan.…”

Section: Introductionmentioning

confidence: 99%

Frequency of hyperlipidemia in patients with ischemic stroke visiting at a tertiary care hospital in Karachi

Bushra Ammad Taimuri,

Abdul Malik,

Rabia Sana Muhammad

et al. 2023

PJNS

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Background and objective: Stroke is the second leading cause of death and the third leading cause of disability. This study was designed to determine the frequency of hyperlipidemia in patients with ischemic stroke visiting at a tertiary care hospital in Karachi. Methods: This was a descriptive cross-sectional study and was done in Department of Medicine, LCMD/ Dar-ul-Sehat Hospital Karachi, Pakistan. A total of 184 patients were studied during the study period of six months and all the consecutive patients were recruited who presented with acute stroke in the department of medicine from the duration April 1st 2022 to September 30th, 2022.Those fulfilling the inclusion criteria for this study were included for data analysis, while the patients who did not meet the said criteria were excluded. Their serum lipid levels were collected within 24 hours of admission. Hyperlipidemia was measured through fasting lipid profile and was labeled as present if any one or more of the following profile like total cholesterol >200 mg/dl, LDL cholesterol > 100 mg/dl, TGL > 150 mg/dl, HDL cholesterol < 40 mg/dl, as appropriate. Results: The mean age of the patients was 65.17±12.73. Average systolic and diastolic blood pressure was 152.34±21.31 & 83.35±13.71 mm Hg respectively. Mean duration of smoking and diabetes mellitus in first ever ischemic stroke patients was 9.33±4.03 & 13.65±5.8 years respectively, whereas average fasting blood sugar was found 151.98±69.73mg/dl; 118 (64%) were males and 66 (36%) were females. A total of 124 (67.4%) of patients had a history of hypertension, while 94 (51.1%) were diabetic. Fifty-three (28.8%) of patients had a history of coronary artery disease while 22 (11.95%) patients had history of smoking. Increased triglycerides level was seen in 47 (25. 5%). The frequency of hyperlipidemia was 145 (79%) patients respectively. Conclusion: Frequency of hyperlipidemia was 145 (79%) in patients with ischemic stroke which is moderately high in our setup. A high prevalence of hyperlipidemia is alarming in our setup and requires attention of the physicians on modifiable risk factors.

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Frequency of Dyslipidemia in Ischemic Stroke Patients Presented to Tertiary Care Hospital of Lahore

Cited by 4 publications

References 21 publications

Hydatidiform Mole Types and Age Demographics in Sindh Province, Pakistan

Hydatidiform Mole Types and Age Demographics in Sindh Province, Pakistan

Frequency of Dyslipidemia in Ischemic Strokes Involving Different Regions of Brain

Frequency of hyperlipidemia in patients with ischemic stroke visiting at a tertiary care hospital in Karachi

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