Frequency and severity of vasomotor symptoms among peri- and postmenopausal women in the United States

Williams, RE; Kalilani, Linda; DiBenedetti, Dana; Zhou, Xiaolei; Granger, Arthur L.; Fehnel, Sheri; Levine, Kristen B.; Jordan, Jamie C.; Clark, Richard V.

doi:10.1080/13697130701744696

Cited by 149 publications

(113 citation statements)

References 29 publications

Supporting

Mentioning

100

Contrasting

Unclassified

Order By: Relevance

“…59 Although the prevalence of HFs has increased in Japan, however, it is still lower than in most Western populations. 16,27,59 These findings, along with those from other studies, such as SWAN, 10,27,52,60 allude to an important observation that race=ethnicity may not independently explain HF prevalence, as no statistically significant association was found between ethnicity=race and HFs after adjustments for such covariates as lifestyle, BMI, smoking, menopausal status, and health-related quality of life.…”

mentioning

confidence: 64%

“…As a result of a longitudinal prospective study, Freeman et al 12 reported that the risk of HFs increased throughout the menopausal transition and was greatest in postmenopausal women (odds ratio [OR] 2.87, 95% confidence interval [CI] 1.76-4.67, p < 0.001). In addition, VMS were most strongly related to the late menopausal transition stage in all racial=ethnic groups 10,14,16,17 and nearly as strongly related to postmenopause, even after adjusting for covariates, 10,12,[18][19][20][21][22] as reported in several other published cross-sectional, 10,[16][17][18]20,22 longitudinal prospective, 12,21 and review 14,19 23 Therefore, when performing analysis on factors that affect the incidence or severity of HFs, the nomenclature of the menopausal stages should be introduced along with other covariates in the final multivariate analysis. In summary, the menopausal stages (mainly the menopausal transition and postmenopause) are strongly associated with HFs, but there is still no single menopausal stage that has been identified as the critical time point for experiencing HFs.…”

Section: The Menopausal Stagesmentioning

confidence: 80%

See 1 more Smart Citation

Factors That May Influence the Experience of Hot Flushes by Healthy Middle-Aged Women

Ziv‐Gal¹,

Flaws

2010

Journal of Women's Health

View full text Add to dashboard Cite

Background: Interest in menopausal symptoms in general and hot flushes (HFs) in particular has grown in recent years. This is mostly due to increased awareness and the vast impact these symptoms have on women's lives. Despite the high prevalence of women who experience HFs, a definitive etiology for HFs is yet to be found. Our objective was to review the current literature dealing with associated factors for experiencing HFs and to provide a synthesized overview on this common and often debilitating condition. Methods: We systematically searched the English-language literature in the PubMed database using relevant key words and included only those articles that contained information on associated factors for HFs in generally healthy midlife women. Results: Both conflicting scientific results between studies documenting factors that influence HFs and the lack of validated measuring tools make it difficult to truly pinpoint associated factors for HFs. Nonetheless, we identified the following clusters of associated factors: the menopausal stages, sex steroid hormones, other endocrine agents, genetic polymorphisms, race=ethnicity, body mass index (BMI) and obesity, mood disorders, smoking, soy isoflavones and phytoestrogens, alcohol consumption, and physical activity. Conclusions: No single associated factor was consistently identified as having a major role in experiencing HFs. More resources should be directed to develop a unified study system along with multivariable analyses to get a better understanding of this condition, which often imposes a tremendous social and personal toll on the women who experience it.

show abstract

mentioning

confidence: 64%

Section: The Menopausal Stagesmentioning

confidence: 80%

Factors That May Influence the Experience of Hot Flushes by Healthy Middle-Aged Women

Ziv‐Gal¹,

Flaws

2010

Journal of Women's Health

View full text Add to dashboard Cite

show abstract

“…This is likely because at baseline women in the SWAN study were required to have had a menstrual period in the past 3 months, suggesting perimenopause, a time when women are more likely to have VMS. 46 The majority of our sample, however, was postmenopausal. Our lower estimate may also reflect our more stringent definition of VMS.…”

Section: Figmentioning

confidence: 99%

The Impact of Multimorbidity on Quality of Life Among Midlife Women: Findings from a U.S. Nationally Representative Survey

Lang¹,

Alexander²,

Simon³

et al. 2015

Journal of Women's Health

View full text Add to dashboard Cite

Background: Little is known about the prevalence and cumulative burden of coexisting health conditions including chronic joint and muscular pain, urinary incontinence (UI), depression, osteoporosis risk, moderate/ severe vasomotor symptoms, and vulvar/vaginal atrophy (VVA). We surveyed a nationally representative U.S. sample of midlife (age 40-64 years) women to ascertain the prevalence, general health-related quality of life (HRQoL), and health-seeking behaviors associated with these six conditions. Methods: This cross-sectional, telephone survey collected data from a sample of English-and Spanish-speaking U.S. women. The survey contained demographic and menopausal status questions, and also five conditionspecific symptom/disease risk-screening instruments. The EuroQol 5 dimensions (EQ-5D) questionnaire was used to measure HRQoL. Health-seeking behavior was measured based on clinician discussion of and recent treatment for each condition. Results: Three thousand fifty eight women (mean age 53.4 years) completed the survey. The majority were white (75.6%), married (60.5%), employed full-or part-time (59.0%), and postmenopausal (69.8%; based on self-report). The prevalence [95% confidence interval] of 0, 1, 2, and ‡ 3 conditions was 35.2% [33.5-36.9], 34.2% [32.5-35.9], 17.9% [16.6-19.3], and 12.7% [11.5-13.9], respectively. Osteoporosis risk (30.6%) was most prevalent, followed by VVA (27.8%) and UI (26.6%). UI and VVA coexisted most frequently (11.3%), followed by osteoporosis risk and VVA (9.8%). EQ-5D scores decreased with increasing number of illnesses (0, 1, 2, and ‡ 3 conditions, means: 0.92, 0.87, 0.77, 0.61, respectively; p < 0.01). Health-seeking behavior varied by condition. Conclusion: Over 25% of women surveyed had multiple coexisting conditions. Lower HRQoL was associated with multiple conditions and with each added condition.

show abstract

“…Analiza wyników doniesień naukowych pozwoliła na sformułowa-nie wniosku, że istnieje grupa objawów, które w okresie okołomenopauzalnym są szczególnie mocno odczuwane przez kobiety, powodują dyskomfort oraz wyraźnie wpływają na kondycję psychofizyczną i działalność społeczno-zawodową kobiet [5][6][7][22][23][24][26][27][28][29][30][31]. Spektrum obejmuje objawy od dyskomfortu aż do stanu wymagającego interwencji lekarskiej.…”

Section: Wynikiunclassified

“…Szacuje się, że objawy wypadowe mogą dotyczyć nawet 75% kobiet w wieku okołomenopauzalnym [5]. Wśród objawów o podłożu somatycznym najczęściej występują uderzenia gorąca [4,[26][27][28][29][30], zaburzenia snu [4,22,23,29,31] i zwiększona potliwość [4,27].…”

Section: Omówienieunclassified

Analysis of relationships between perimenopausal symptoms and professional functioning and life satisfaction – Subjective perception of the dependence in women aged 40+

Nowakowska¹,

Rasińska²,

Głowacka³

2015

Med Pr

View full text Add to dashboard Cite

StreszczenieWstęp: W pracy przedstawiono analizę opinii kobiet w wieku okołomenopauzalnym o subiektywnie odczuwanych objawach charakterystycznych dla okresu klimakterycznego, które mają związek z funkcjonowaniem zawodowym, oraz ocenę wpływu wybranych zmiennych na występowanie i nasilenie odczuwania tych objawów i poczucie satysfakcji z życia. Materiał i metody: Badaniem objęto 250 aktywnych zawodowo kobiet w wieku okołomenopauzalnym (40-57 lat) mieszkających w dużych miastach. W badaniu wykorzystano Skalę Satysfakcji z Życia (Satisfaction with Life Scale -SWLS) do oceny poczucia zadowolenia z życia oraz Indeks Kuppermana (IK) do samodzielnej ilościowej i jakościowej oceny objawów klimakteryjnych. Wykorzystano także opacowany przez prowadzących badanie kwestionariusz zawierający indeks zdefiniowanych objawów okresu okołomenopauzal-nego, dzięki któremu można było przeprowadzić analizę Pareto-Lorenza. Wyniki: Wyniki świadczą o statystycznie istotnej zależności między występowaniem i nasileniem objawów menopauzalnych (według IK) a miejscem pracy kobiet (p = 0,04912), opieką ginekologiczną (p = 0,00325), stosowaniem hormonalnej terapii zastępczej (HTZ) (p = 0,01523) oraz oceną zadowolenia z życia (p = 0,0325). Po przeanalizowaniu wyników za pomocą analizy Pareto-Lorenza okazało się, że kobiety wskazały uderzenia gorąca, rozdrażnienie, obniżoną koncentrację i koordynację, zaburzenia snu oraz zwiększoną potliwość jako objawy szczególnie wpły-wające na efektywne funkcjonowanie zawodowe i powodujące dyskomfort. Wnioski: Istnieje wyraźna, statystycznie istotna zależność między miejscem pracy kobiet, opieką ginekologiczną, stosowaniem HTZ oraz oceną satysfakcji z życia a nasileniem objawów występujących w okresie okołomenopauzalnym. Zaobserwowano zespół objawów, których obecność i nasilenie wpływają na poczucie zadowolenia z życia i ocenę funkcjonowania zawodowego. Kobiety jako objawy okresu menopauzalnego utrudniają-ce im funkcjonowanie zawodowe najczęściej wskazują uderzenia gorąca, rozdrażnienie, obniżoną koncentrację i koordynację, zaburzenia snu oraz zwiększoną potliwość. Med. Pr. 2015;66(3):351-358 Słowa kluczowe: aktywność zawodowa, satysfakcja z życia, objawy klimakterium, wiek okołomenopauzalny, menopauza, satysfakcja osobista Abstract Background: The aim of the study was to analyse and present the opinions of women in perimenopause on subjectively perceived symptoms characteristic of the climacteric period, and connected with their professional functioning, as well as to evaluate the effects of selected variables on the incidence and severity of these symptoms and the women's life satisfaction. Material and Methods: The study included 250 professionally active women in perimenopausal age (40-57 years). The study used the Satisfaction with Life Scale (SWLS) to evaluate life satisfaction of women and the Kupperman Index (KI) as quantitative and qualitative self-assessment of climacteric symptoms. The authors also used a questionnaire of their own design that contains an index of defined symptoms of perimenopause...

show abstract

Frequency and severity of vasomotor symptoms among peri- and postmenopausal women in the United States

Abstract: The Menopause Epidemiology Study builds upon existing literature by providing data on daily frequency and severity of vasomotor symptoms. There are many women with frequent and severe vasomotor symptoms who may benefit from treatment.

Cited by 149 publications

References 29 publications

Factors That May Influence the Experience of Hot Flushes by Healthy Middle-Aged Women

Factors That May Influence the Experience of Hot Flushes by Healthy Middle-Aged Women

The Impact of Multimorbidity on Quality of Life Among Midlife Women: Findings from a U.S. Nationally Representative Survey

Analysis of relationships between perimenopausal symptoms and professional functioning and life satisfaction – Subjective perception of the dependence in women aged 40+

Contact Info

Product

Resources

About