2008
DOI: 10.1016/j.fct.2008.06.062
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Fragrance material review on nerol

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Cited by 27 publications
(20 citation statements)
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“…The acute oral LD50 of NEL was evaluated to be 4.5 g/kg in Wistar rats, which indicated that it is safe (Lapczynski, Foxenberg, Bhatia, Letizia, & Api, 2008). In addition, NEL is abundant and its use worldwide is in the region of 100e1000 metric tonnes per annum (Lapczynski et al, 2008), showing its potential as a plant-based preservative in food industrials.…”
Section: Discussionmentioning
confidence: 99%
“…The acute oral LD50 of NEL was evaluated to be 4.5 g/kg in Wistar rats, which indicated that it is safe (Lapczynski, Foxenberg, Bhatia, Letizia, & Api, 2008). In addition, NEL is abundant and its use worldwide is in the region of 100e1000 metric tonnes per annum (Lapczynski et al, 2008), showing its potential as a plant-based preservative in food industrials.…”
Section: Discussionmentioning
confidence: 99%
“…NEL has a sweet rose odor and is originally from essential oil which are classified as “generally regarded as safe” (GRAS) by the United State Food and Drug Administration (FDA) [15]. Some acute toxicity tests for oral, dermal, and intramuscular have proved that NEL is very safe, for example, the acute oral LD50 of NEL was evaluated to be 4.5 g/kg by Wistar rats [5]. Moreover, NEL are abundant and its use worldwide is in the region of 100–1000 metric tonnes per annum [5], which makes NEL suitable for development into a natural food preservative.…”
Section: Discussionmentioning
confidence: 99%
“…Some acute toxicity tests for oral, dermal, and intramuscular have proved that NEL is very safe, for example, the acute oral LD50 of NEL was evaluated to be 4.5 g/kg by Wistar rats [5]. Moreover, NEL are abundant and its use worldwide is in the region of 100–1000 metric tonnes per annum [5], which makes NEL suitable for development into a natural food preservative.…”
Section: Discussionmentioning
confidence: 99%
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“…To be mentioned that nerol is found in various medicinal plants, those are reported to have significant antioxidant, antimicrobial and neuroprotective activities [8][9][10]. Furthermore, nerol is used as a fragrance in cosmetics and toiletries [11].…”
Section: Introductionmentioning
confidence: 99%