Four new monoterpenoids from an endophytic fungus Periconia sp. F-31

Abstract

Five monoterpenoids were isolated from the endophytic fungus Periconia sp. F-31, including three new carene-type monoterpenoids, 2-carene-5,8-diol (1), 2-carene-8,10-diol (2), 2-carene-8-acetamide (3), one new menthene-type monoterpenoid 8-hydroxy-1,7-expoxy-2-menthene (4), and one known monoterpenoid anethofuran (5). The structures of all compounds were elucidated based on a comprehensive spectroscopic data analysis, electronic circular dichroism (ECD), and calculated ECD.

Natural Products Containing the Oxetane and Related Moieties Present Additional Challenges for Structure Elucidation: A DU8+ Computational Case Study

“…A new monoterpenoid from the endophytic fungus Periconia sp. F-31, 8-hydroxy-1,7expoxy-2-menthene, 39 is revised to its thf isomer. A highly oxygenated abietane diterpenoid triptergulide A, isolated from the leaves of Tripterygium wilfordii, 40 is perhaps not as deeply rearranged as the authors hypothesized.…”

Progress on Terpenoids With Biological Activities Produced by Plant Endophytic Fungi in China Between 2017 and 2019

“…F-31, which was separated from the medicinal plant Annona muricata, is distributed in the Hainan Province, China. 23 The structures of these monoterpenoids are displayed in Figure 1.…”

Phenolic Compounds from Endophytic Pseudofusicoccum sp. Isolated from Annona muricata

“…A. muricata have been studied for the bioactive natural products produced by its endophytic fungal populations. [14][15][16][17][18][19][20][21][22][23] 14,15,17 and sesquiterpenes: periconianones C-K. 19 Secondary metabolites of endophytic fungi of A. muricata showed anticancer activities. 22,23 Periconiasins A and B showed significant cytotoxicity against human colon cancer cells (HCT-8).…”