Abstract:Background:Nicotine replacement therapy (NRT) with gradual decreasing of nicotine is one of the smoking cessation methods. Muccoadhesive formulations are among the novel drug delivery systems that are available in the form of tablets and films, and can be used for NRT. Muccoadhesive nicotine tablets when placed in the upper gum will attach to the buccal mucosa and release nicotine content in a controlled manner. This will meet the immediate and long-term need of the individual to the nicotine, such that the pe… Show more
“…pH was then noted by bringing the electrode near the surface of the formulation and allowing equilibrating for 1 min. The experiments were carried out in triplicate [7] .…”
“…pH was then noted by bringing the electrode near the surface of the formulation and allowing equilibrating for 1 min. The experiments were carried out in triplicate [7] .…”
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