FORMULASI DAN EVALUASI SALEP EKSTRAK DAUN GULMA SIAM (Chromolaena odorata L.) DENGAN VARIASI BASIS SALEP

Abstract

Siam weed leaves are one of the plants that function as wound medicine. This study aims to produce a stable ointment dosage form. Siamese weed leaf extract is formulated in the form of ointment with a variety of bases consisting of a hydrocarbon base, absorption, water soluble and emulsion. Evaluation of physical stability includes organoleptic testing, homogeneity, pH, dispersion, viscosity and flow properties carried out before and after forced conditions. Forced conditions were carried out with stock storage for 10 cycles at 50 and 350. The results of the analysis showed that the viscosity of the preparations in all formulas changed after storage at 50 and 350 for 5 days. However, the statistical results show that all formulas did not experience significant changes between before and after the stress condition treatment.

Accelerated stability test of snakehead fish and kelulut honey ointment with CMC-Na as a binder

“…A homogeneous ointment characterized by the absence of lumps on the result of basting, even structure, and a uniform color (Hasrawati et al, 2019). The control formulation produced an inhomogeneous preparation on the 7th day which was marked by the presence of phase separation.…”

“…Homogeneity testing is done by applying 0.1 gram of ointment to the surface of the object-glass and then observing its homogeneity. A homogeneous ointment characterized by the absence of lumps on the result of basting, even structure, and a uniform color (Hasrawati et al, 2019).…”

Formulation and Evaluation of Ointment Preparations with Nutgrass Extract (Cyperus rotundus L.) Using Different Ointment Bases

“…Uji kestabilan salep ekstrak tumbuhan teki dengan jenis basis salep yang berbeda dilakukan sebelum dan sesudah penyimpanan dalam suhu kamar selama 7 hari (Hasrawati et al, 2019).…”

The Formulation and Stability Test of The Balm Emprit Ginger (Zingiber officinale var. amarum) Essential Oil

“…Apa bila daya lekat semakin besar maka waktu kontak antara sediaan dengan kulit akan semakin lama, sehingga proses absorbsi obat melalui kulit samakin besar. Adapun syarat waktu daya lekat yang baik adalah tidak kurang dari 4 detik [14].…”

“…Daya lekat yang baik memungkinkan obat tidak mudah hilang dan semakin lama melekat pada kulit oleh karena itu sediaan dapat menghasilkan efek yang diinginkan. Syarat waktu daya lekat yang baik adalah tidak kurang dari 4 detik [14].…”