Th is paper explores the state and pace of the development of science and innovation policy in Russia with the goal of fi nding an explanation for its relatively slow progress. We argue that this slow pace can be explained by three major factors. First, instruments of science and innovation policy are government-centered as manifested in excessive, hands-on government involvement. Th is is a refl ection of the vertically organized Russian innovation system having weak horizontal linkages. Second, the government policy is poorly balanced. While in some areas there is a policy mix, in others, necessary instruments are lacking. Th is is a result of a growing asymmetry of information under the conditions of weak horizontal linkages. Th ird, in recent years, changes in economic conditions and international relations started to aff ect Russia's innovation system. Measures undertaken in response to economic sanctions produced signals that confl ict with the science and innovation policy. We illustrate our position by analyzing (1) policy instruments aimed at linking research and commercialization and supporting the improvement of the scientifi c and technological workforce, and (2) new regulations, which appeared during economic sanctions and are related to the work of foreign science foundations in Russia.We link our interpretations to theoretical studies of science and innovation policy and a policy mix. Th e Russian case confi rms the theoretical models that describe hierarchical systems in which government dominates and asymmetry of information becomes a persistent problem. Government, as a principal, tries to fi nd new forms of a pursuing agent to implement tasks. In Russia, the lack of monitoring leads to new instruments being added while the existing ones remain uncorrected. As a result, a policy mix becomes more complex and its outcomes are diffi cult to predict.