Food intake and body weight in rats with daily food-availability restrictions

Krízová, E; Šimek, Vladimír; Abelenda, M.; Puerta, Marisa

doi:10.1016/0031-9384(96)00161-8

Cited by 5 publications

(2 citation statements)

References 9 publications

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“…A previous study showed that the body weight of a PO-induced hyperuricemia mouse model was significantly lower than that of control rats [28], which is similar to Table 1 of this study. More precisely, not only body weight, but also the results of food intake and water consumption records, were still within the physiological ranges of normal rats [29,30]. In the organ weight results of Table 2, the livers and spleens of PO-induced rats were significantly heavier than those of the control group (p < 0.05), and the weight of the perirenal fat tissue of PO-induced rats was significantly lighter than that of the control group (p < 0.05).…”

Section: Discussionmentioning

confidence: 79%

Supplementation of Lactobacillus plantarum (TCI227) Prevented Potassium-Oxonate-Induced Hyperuricemia in Rats

Chien

Lin³

et al. 2022

Nutrients

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Hyperuricemia (HC) is one of the important risk factors for gout, arteriosclerosis, and cardiovascular disease. Animal studies have shown that Lactobacillus plantarum can improve microbiota and immune regulation, as well as inhibit uric acid production. However, it is not clear whether L. plantarum can improve HC and intestinal microbiota. We used potassium oxonate (PO) to induce HC in male SD rats and then treated them with L. plantarum TCI227 in a dose-dependent manner (HC + LD, HC + MD, HC + HD) for 4 weeks. We examined organ weight, conducted biochemical examinations of blood and urine, and analyzed the intestinal microbiota in feces through a 16s rDNA sequence analysis. In this study, TCI227 improved body weight, decreased creatinine and serum uric acid, and increased urine uric acid compared to the HC group. Furthermore, TCI227 increased short-chain fatty acids (SCFAs). In the fecal microbiota (family), TCI227 increased the level of Lactobacillaceae and then decreased the levels of Deferribacteres and Prevotellaceae compared to the HC group. Finally, in the fecal microbiota (genus), TCI227 decreased the level of Prevotella and then increased the levels of Lactobacillus and Ruminococcus compared to the HC group. This study suggested that TCI227 can improve HC and can change the composition of intestinal microbiota in PO-induced male HC SD rats.

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Section: Discussionmentioning

confidence: 79%

Supplementation of Lactobacillus plantarum (TCI227) Prevented Potassium-Oxonate-Induced Hyperuricemia in Rats

Chien

Lin³

et al. 2022

Nutrients

View full text Add to dashboard Cite

show abstract

“…The previous study showed that the body weight of the PO-induced hyperuricemia mouse model was significantly lower than that of the control rats [28], which is similar to the Table 1 of this study. More precisely, not only body weight, but also the results of food intake and water consumption records are still within the physiological range of normal rats [29,30]. In the organ weight result of Table 2, the liver and spleen of PO-induced rats were significantly heavier than the control group (p < 0.05), and the weight of the perirenal fat tissue of PO-induced rats was significantly lighter than the control group (p < 0.05).…”

Section: Discussionmentioning

confidence: 99%

Supplementation of <em>Lactobacillus Plantarum</em> (TCI227) Prevented Potassium Oxonate Induced Hyperuricemia in Rats

Chien¹,

Chien²,

Lin³

et al. 2022

Preprint

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Hyperuricemia (HC) was one of the important risk factors for gout, arteriosclerosis, and cardiovascular disease. Animal studies have shown that Lactobacillus plantarum can improve the microbiota, immune regulation, and inhibit the uric acid production. However, it was not clear whether L. plantarum can improve HC and intestinal microbiota. We used potassium oxonate (PO) to induce HC in male SD rats, and then treated L. plantarum TCI227 in a dose dependent (HC+LD, HC+MD, HC+HD) for 4 weeks, and examined weight organs, biochemical examination of blood and urine, and analyzed the intestinal microbiota in feces by 16s rDNA sequence analysis. In this study, TCI227 improved body weight, decreased creatinine, serum uric acid, and increased urine uric acid compared to the HC group. Furthermore, TCI227 increased short-chain fatty acids (SCFAs). In fecal microbiota (family), TCI227 increased the level of Lactobacillaceae, and then decreased the level of Deferribacteres and Prevotellaceae compared to the HC group. Finally, in fecal microbiota (genus), TCI227 decreased the level of Prevotella, and then increased the level of Lactobacillus and Ruminococcus compared to the HC group. This study suggested that TCI227 can improve HC and change the compositions of the intestinal microbiota in PO induced male HC SD rats.

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Intermittent fasting promotes anxiolytic-like effects unrelated to synaptic mitochondrial function and BDNF support

Carteri

Menegassi

Feldmann

et al. 2021

Behavioural Brain Research

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Food intake and body weight in rats with daily food-availability restrictions

Cited by 5 publications

References 9 publications

Supplementation of Lactobacillus plantarum (TCI227) Prevented Potassium-Oxonate-Induced Hyperuricemia in Rats

Supplementation of Lactobacillus plantarum (TCI227) Prevented Potassium-Oxonate-Induced Hyperuricemia in Rats

Supplementation of <em>Lactobacillus Plantarum</em> (TCI227) Prevented Potassium Oxonate Induced Hyperuricemia in Rats

Intermittent fasting promotes anxiolytic-like effects unrelated to synaptic mitochondrial function and BDNF support

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