Folic Acid Functionalized Vertically Aligned Carbon Nanotube (FA-VACNT) Electrodes for Cancer Sensing Applications

Carbon nanotubes assisted analytical detection – Sensing/delivery cues for environmental and biomedical monitoring

“…This disease has become caused of countless death around the globe therefore several efforts were put to reduce the effect of this disease in the recent times. In this connection CNTs have been reported for the development of fast and effective detection as well as treatment tool of several cancer diseases [57][58][59][60]. Zanganeh et al ( 2016), [57] developed an electrical biosensor for detection of cancer cells.…”

“…In this connection CNTs have been reported for the development of fast and effective detection as well as treatment tool of several cancer diseases [57][58][59][60]. Zanganeh et al ( 2016), [57] developed an electrical biosensor for detection of cancer cells. The CNTs were conjugated to folic acid (FA-VACNTs) molecules.…”

“…The FA-VACNT electrodes showed better electrical response of the sensors. This device could be applied to detect and monitor cancer [57]. The nanohybrid microelectrode has shown good detection performance for H2O2 with efficient structural mechanics integrated with electrochemical properties.…”

Emergence in the functionalized carbon nanotubes as smart nanocarriers for drug delivery applications

“…This process of cancer treatment is generally referred to as Photothermal Therapy. Similarly, MWCNTs doped with nitrogen gas have been found to induce thermal ablation causing death of cancer cells upon irradiation with an infrared light source (Zanganeh et al, 2016). It can accordingly be concluded that the antitumor activity of CNTs might be due to heat transduction, which leads to less cellular cytotoxicity.…”

A label-free graphene-based impedimetric biosensor for real-time tracing of the cytokine storm in blood serum; suitable for screening COVID-19 patients

“…To improve electrochemical interface between biological macromolecules (such as cytokines) and electrodes, nanomaterials would be the best choice. 26 Among famous mostly used biosensing electrodes including MWCNT, 27 SiNWs 28 and graphene 29,30 we used graphene sheets deposited on a copper substrate due to their better charge mobility 31 and electrical conductivity. 32 Moreover, graphene showed much better site binding with polarizable bio-agents as we investigated IL-6 cytokine using MD simulation.…”