Focal infection

Galloway, Charles Edwin

doi:10.1016/s0002-9610(31)91140-9

Cited by 24 publications

(21 citation statements)

References 1 publication

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“…It is reasonable to suggest that infection of the gingiva and periodontium by Gram-negative anaerobic bacteria provide a reservoir for microbial products (e.g., LPS) and sufficiently challenge the host to produce responses which may be deleterious to both the pregnant mother and the fetus. 212 In addition, a non-causal correlation between periodontal disease and PTB has been hypothesized where hyper-inflammatory response to bacterial challenge is genetically determined. 213 As demonstrated in these studies, the association between bacterial colonization and maternal host responses remain speculative.…”

Section: Discussionmentioning

confidence: 99%

Oral colonization of Gram-negative anaerobes as a risk factor for preterm delivery

Africa¹

2011

Virulence

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Section: Discussionmentioning

confidence: 99%

Oral colonization of Gram-negative anaerobes as a risk factor for preterm delivery

Africa¹

2011

Virulence

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“…Galloway 5 reported in 1931 that focal infection in teeth and tonsils affected the fetus. His was probably the first interventional study.…”

Section: What the Research Showsmentioning

confidence: 99%

Periodontal Infections and Adverse Pregnancy Outcomes: The Oral Health—Fetal Connection

Avula¹,

Jayakumar²

2011

Journal of Gynecologic Surgery

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Objective: The increasing awareness of the relationship between maternal oral health and adverse pregnancy outcomes is well documented in the dental literature.The present review aims at summing up the current state of evidence and research on the same and sharing the available literature with the obstetric and other general practitioners so that the patients are diagnosed and treated with an interdisciplinary approach. Materials and methods: A search of the dental literature, including Medline Ò =PubMed through 2009, was conducted focusing on periodontal disease, preterm delivery, low birth weight, and intrauterine growth restriction was undertaken, and a hand search of other gray literature and text books was performed. Conclusions: It has been widely reported that pregnant women with periodontitis have more chances of having adverse pregnancy outcomes such as preterm birth, low birth-weight infants, preeclampsia, gestational diabetes, small-for-gestational age infants, and fetal loss. At the same time, there have been sporadic reports that contradict this potential association. Clinicians need to remain abreast with available and emerging information, and exercise prudence while considering the possible adverse pregnancy outcomes from chronic periodontal infections. ( J GYNECOL SURG 27:1)

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“…Given the considerable effect of pregnancy on oral health it is interesting that the impact of periodontal disease on pregnancy outcome is now under scrutiny. The idea that it may contribute to pregnancy outcome was presented in 1931 when Galloway 18 stated that periodontal disease may provide ‘sufficient infectious microbial challenge’ to have ‘potentially harmful effects on the pregnant mother and developing fetus’. Infection, especially symptomatic infection of the genitourinary tract, is considered an important risk factor for preterm birth and/or low birthweight.…”

Section: The Impact Of Periodontal Health On Pregnancymentioning

confidence: 99%

Dental manifestations of pregnancy

Pirie

Cooke

Linden

et al. 2007

The Obstetric & Gynaecologis

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Key content Pregnancy has significant effects on the periodontal tissues and pregnancy gingivitis is a common manifestation of this. The host response and oral flora are affected and tooth surface loss and mobility may develop. Further research is required to establish the association between periodontal health and adverse pregnancy outcome. Learning objectives To identify the main dental manifestations of pregnancy. To be able to advise pregnant women on how to maintain good dental health. To be aware of the need for effective communication between the dental and medical disciplines to ensure that pregnant women receive the best care possible for oral, obstetric and general health. Ethical issues The treatment of gingivitis and periodontitis during pregnancy is safe and effective in treating gum disease. Please cite this article as: Pirie M, Cooke I, Linden G, Irwin C. Dental manifestations of pregnancy. The Obstetrician & Gynaecologist 2007;9:21–26.

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Focal infection

Cited by 24 publications

References 1 publication

Oral colonization of Gram-negative anaerobes as a risk factor for preterm delivery

Oral colonization of Gram-negative anaerobes as a risk factor for preterm delivery

Periodontal Infections and Adverse Pregnancy Outcomes: The Oral Health—Fetal Connection

Dental manifestations of pregnancy

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