FluosolR Da and Oxygen as an Adjuvant to the Radiotherapeutic Management of Advanced Head/Neck Carcinoma

Lustig, Robert A.; Rose, Christopher M.; McIntosh-Lowe, Norma

doi:10.3109/10731198809132606

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Cancer Therapy1

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1989

1998

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Cited by 6 publications

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“…This arises as a result of abnormal vasculature and consequent inadequate blood flow. PFC emulsions have been used with varying degrees of success to increase tumour oxygenation and thus, sensi tize them to either radiation or chemotherapy [34,38,85,86]. It is noteworthy that PFC emulsions developed for their cancer therapy-enhancing properties (i.e.…”

Section: Cancer Therapymentioning

confidence: 99%

Synthetic Oxygen Transport Fluids Based on Perfluorochemicals: Applications in Medicine and Biology

Lowe¹

1991

Vox Sanguinis

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Recent advances in the development and assessment of synthetic oxygen transport fluids based on perfluorochemicals (PFCs) are reviewed. The basic properties of PFCs are outlined, together with the selection criteria for biomedical applications. PFCs must be emulsified for intravascular use and attention is focussed on the formulation and biocompatibility testing of both first- and second-generation emulsions and their components in man and other species. The multidisciplinary applications for PFCs in medicine and basic biomedical research are described, including the clinical use of Fluosol-DA 20% as an oxygen-carrying perfusate in percutaneous transluminal coronary angioplasty.

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Section: Cancer Therapymentioning

confidence: 99%