Fluoride Levels in Dentin after Iontophoresis of 2% NaF

Abstract

The fluoride in successive layers of dentin (from 3-6 micron were removed per etch) has been measured following topical or iontophoretic application of 2% aqueous sodium fluoride to coronal exposed dentin of freshly extracted human third molar teeth. The fluoride contents of the topical and iontophoresed first etches were, respectively, 12 and 22-31 times greater than that of control (untreated) teeth. Similarly, the fourth etches were 12 and 50-70 times greater, and the seventh (last sampled) etches were 5 and 28-41 times greater. There was no apparent change in acid solubility of the dentin as its fluoride content varied under the conditions of this study. This is the first report studying the fluoride content of extremely thin layers of dentin successively removed by acid etch and relating topical to iontophoretic uptake.

Comparison of remineralization effect of three topical fluoride regimens on enamel initial carious lesions

“…The findings support those obtained by previous studies. 14,15,30,31 However, the remineralization effect of iontophoresis NaF was significantly lower than that of APF gel. Recently, APF gel has become popular among dental practitioners and is known to be an effective method for reducing the incidence of dental caries.…”

Effect of fluoride iontophoresis on the microtensile bond strength between dentin and two adhesive systems

“…These ions chemically react with free calcium ions, in particular from the dentinal fluid, forming acid-resistant calcium fluoride that occludes the tubules to varying extents. 28 There is a direct relationship between the frequency and duration of fluoride ionophoresis treatment and the size, form and depth of occluding-particle penetration in the tubules. 29 SEM photomicrographs showed that treatment of the specimens with 6% citric acid for 2 min in an ultrasonic bath effectively removed the dentin smear layer, creating a smooth surface with exposure of dentinal tubule orifices (Fig.…”

The Influence of Different Power Settings of Nd:YAG Laser Irradiation, Bioglass and Combination to the Occlusion of Dentinal Tubules

“…NaF is used widely, yielding predictable positive results in many cases. 13 Additionally, iontophoresis has been shown to increase the uptake of F. 14 A novel treatment has been developed to treat CDH. In NovaMin Ò (NM) (Denshield, NovaMin Ò Technology, FL), the active ingredient is a bioactive glass that has been ground into a fine particulate with a median size of < 20 lm, composed of Ca, P, Na, Si, and O.…”