Fluoride - an adjunctive therapeutic agent for periodontal disease? Evidence from a cross-sectional study

Kumar, Santhosh; Sharma, Jyothi; Duraiswamy, Prabu; Kulkarni, Suhas

doi:10.4317/medoral.14.e547

Cited by 3 publications

(3 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Authors have reported no association between periodontal parameters and fluorosis,[ 19 20 21 ] increased periodontal scores,[ 22 23 ] and reduced periodontal scores. [ 24 25 26 27 28 ] Further, significant differences in response to various nonsurgical therapeutic modalities exist between fluorosed versus nonfluorosed roots. [ 29 ] Hence, the association of fluorosis and periodontal tissues is thought provoking.…”

Section: Introductionmentioning

confidence: 99%

Fluorosed fibroblast attachment on fluorosed and nonfluorosed teeth after SRP and EDTA root biomodification

Girotra

Vandana

2014

J Indian Soc Periodontol

View full text Add to dashboard Cite

Background:Fluorosis causes mineralization changes in the tooth and can lead to morphologic alterations of fibroblasts. To understand the effect of fluorosis on periodontal healing, the initial step during healing, such as fibroblast attachment to the root surface, needs to be evaluated. Hence, the objective of the present study was to study the attachment of fluorosed fibroblasts on the fluorosed and nonfluorosed root fragments.Materials and Methods:A total of 56 fluorosed and nonfluorosed, periodontally healthy and diseased tooth roots were obtained and allotted to eight groups: Fluorosed and nonfluorosed healthy controls (FH and NFH, respectively), fluorosed and nonfluorosed diseased controls (FD and NFD, respectively), fluorosed and nonfluorosed roots treated with scaling and root planing (FD + S and NFD + S, respectively), and similar groups treated with scaling and root planing and 24% ethylenediaminetetraacetic acid (EDTA) gel application for 2 min (FD + SE and NFD + SE, respectively). After the respective treatment, the root fragments were incubated in the human periodontal ligament fibroblast cells obtained and cultured from freshly extracted healthy human fluorosed premolar tooth root.Results:In the nonfluorosed roots category, greater attachment was found in the untreated nonfluorosed diseased (P = 0.036) and SRP-treated nonfluorosed diseased groups (P = 0.008) as compared to the nonfluorosed healthy group. While in the fluorosed roots category, no significant difference was observed in FL-FA (P > 0.05) within the group. However, no attachment was observed in EDTA-treated fluorosed root fragments. When fluorosed groups were compared to nonfluorosed groups, no significant changes were noted between the groups.Conclusion:SRP proves to be a standard requirement for fibroblast attachment to occur both in fluorosed and nonfluorosed roots. Although there was no significant difference in attachment between SRP and SRP + EDTA among fluorosed roots, EDTA does not seem to be a promising agent for root biomodification in fluorosed roots in a given concentration and time of treatment.

show abstract

Section: Introductionmentioning

confidence: 99%

Fluorosed fibroblast attachment on fluorosed and nonfluorosed teeth after SRP and EDTA root biomodification

Girotra

Vandana

2014

J Indian Soc Periodontol

View full text Add to dashboard Cite

show abstract

“…Di samping itu, kadar fluorida juga diketahui berhubungan dengan kesehatan, khususnya kesehatan gigi dan mulut. Seiring dengan meningkatnya konsentrasi fluorida, tingkat keparahan penyakit periodontal secara signifikan perlahan menurun (33). Kriteria fluorida merupakan hal yang unik karena bergantung pada suhu udara masing-masing daerah (34).…”

Section: Materi Dan Metodeunclassified

Hubungan Kadar Kesadahan dan Fluorida dalam Air Bersih pada Kejadian Penyakit Periodontal di Kecamatan Pundong, Kabupaten Bantul, Yogyakarta

Nur'aini,

Setiawan,

Prihastuti

et al. 2023

Jurnal Kesehatan Lingkungan Indonesia

View full text Add to dashboard Cite

Latar belakang: Penyakit periodontal termasuk masalah kesehatan oral di Indonesia dengan jumlah kasus periodontitis sebesar 74,10% pada tahun 2018. Penyakit periodontal pada tingkat keparahan tinggi dapat menyebabkan kehilangan gigi. Faktor primer penyebab penyakit periodontal adalah plak gigi dan diperkuat oleh keberadaan kalkulus. Terjadinya pembentukan kalkulus dapat meningkat bersama dengan jumlah kalsium dan mineral lainnya dalam saliva termasuk fluorida. Air sumur sebagai sumber air bersih yang digunakan masyarakat mengandung kesadahan dan fluorida. Tujuan penelitian ini adalah untuk mengetahui hubungan kadar kesadahan dan fluorida dalam air bersih pada kejadian penyakit periodontal di Kecamatan Pundong, Kabupaten Bantul, Yogyakarta.Metode: Penelitian ini adalah penelitian observasional analitik dengan desain case control (kasus kontrol). Subjek penelitian sebanyak 120 responden, 60 kasus terdiagnosis penyakit periodontal dan 60 kontrol tidak terdiagnosis penyakit periodontal. Penelitian ini menggunakan data primer berupa sampel air bersih yang diujikan di Balai Laboratorium Kesehatan Yogyakarta, data sekunder berupa data penyakit periodontal dari rekam medis pasien Puskesmas Pundong, Kecamatan Pundong, Kabupaten Bantul Yogyakarta pada tahun 2016. Variabel bebas adalah kadar kesadahan dan fluorida dalam air bersih, variabel terikat adalah penyakit periodontal. Data yang diperoleh diuji menggunakan bivariate Chi Square dengan tingkat signifikansi 0,05 (5%).Hasil: Berdasarkan analisis bivariate, variabel kesadahan tidak berhubungan dengan kejadian penyakit periodontal (p=0,3153; OR=1,16), begitu pula variabel kadar fluorida tidak berhubungan dengan kejadian penyakit periodontal (p=0,1664; OR=1,7).Simpulan: Kadar kesadahan dan fluorida dalam air bersih tidak memiliki hubungan yang signifikan dengan kejadian penyakit periodontal. ABSTRACT Title: Relationship between Hardness and Fluoride Levels in Water with Incidence of Periodontal Disease in Pundong District, Bantul Regency, YogyakartaBackground: Periodontal disease is one of oral health problems in Indonesia with 74.10% of periodontitis cases in 2018. Periodontal disease at high levels of severity can cause tooth loss. The primary factor causing periodontal disease is dental plaque and reinforced by the presence of calculus. The occurrence of calculus formation can increase along with the amount of calcium and other minerals in saliva including fluoride. Well water as a source of clean water used by the community contains hardness and fluoride. The purpose of this study was to determine the relationship between hardness and fluoride levels in water on the incidence of periodontal disease in Pundong District, Bantul Regency, Yogyakarta.Method: This research was analytical observational study with a case control design. The research subjects were 120 respondents, consisting of 60 cases with diagnosis of periodontal disease and 60 controls without diagnosis of periodontal disease. This study used primary data in the form of water samples tested at the Yogyakarta Health Laboratory Center, secondary data in the form of periodontal disease data from medical records of patients at the Puskesmas Kecamatan Pundong, Pundong District, Bantul Regency, Yogyakarta in 2016. The independent variables were fluoride and hardness levels in water, the dependent variable was periodontal disease. The data obtained was tested using Chi Square bivariate with a significance level of 0.05 (5%).Result: Based on bivariate analysis, the hardness variable was not associated with the incidence of periodontal disease (p=0.3153; OR=1.16), as well as the fluoride level variable was not associated with the incidence of periodontal disease (p=0.1664; OR=1, 7).Conclusion: Hardness and fluoride levels in water have no significant relationship with the incidence of periodontal disease.

show abstract

“…Authors have reported no association between periodontal parameters and fluorosis; [12][13][14] increased periodontal scores; [15,16] reduced periodontal scores. [17][18][19][20][21] Based on these reports, the fibroblasts of the fluorosed tooth root which is altered in morphology may influence its attachment to the root surface. The morphology of normal fibroblasts is flat and elongated, which enhance their attachment on root surface.…”

Section: Introductionmentioning

confidence: 99%

Comparative assessment of fluorosed and nonfluorosed fibroblast attachment on fluorosed and nonfluorosed teeth after scaling and root planning and ethylenediaminetetraacetic acid root biomodification

Vandana¹,

Girotra²,

Jayashree³

et al. 2014

J Int Clin Dent Res Organ

View full text Add to dashboard Cite

Fluoride - an adjunctive therapeutic agent for periodontal disease? Evidence from a cross-sectional study

Cited by 3 publications

References 19 publications

Fluorosed fibroblast attachment on fluorosed and nonfluorosed teeth after SRP and EDTA root biomodification

Fluorosed fibroblast attachment on fluorosed and nonfluorosed teeth after SRP and EDTA root biomodification

Hubungan Kadar Kesadahan dan Fluorida dalam Air Bersih pada Kejadian Penyakit Periodontal di Kecamatan Pundong, Kabupaten Bantul, Yogyakarta

Comparative assessment of fluorosed and nonfluorosed fibroblast attachment on fluorosed and nonfluorosed teeth after scaling and root planning and ethylenediaminetetraacetic acid root biomodification

Contact Info

Product

Resources

About