Fluorescent detection of copper(II) based on DNA-templated click chemistry and graphene oxide

Zhou, Lifen; Shen, Qinpeng; Zhao, Peng; Xiang, Bingbing; Nie, Zhou; Huang, Yan; Yao, Shouzhuo

doi:10.1016/j.ymeth.2013.09.001

Cited by 20 publications

(2 citation statements)

References 44 publications

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“…Low detection limit was obtained under the optimal conditions. The specificity of the click chemistry and GO quenching ability revealed low detection limit [28].…”

Section: +mentioning

confidence: 99%

Graphene Oxide for Biomedical Applications

K¹,

Modak²,

Paik³

2017

JNMR

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Graphene oxide (GO) is one of the most promising functional materials used in various applications like energy storage (batteries and supercapacitors) sensors, photocatalysis, electronics and in biomedicine. The last 10 years literature on GO for biomedical applications revealed and confirmed the scope of its potential capabilities as biomaterial. GO alone and its modified form with different materials (surface functionalization, immobilization of nanoparticles and composite formation) also proved as a multifunctional candidate for medical biotechnology. A material for its use in biomedical applications must be biocompatible and nontoxic to the living cells.. Although there are some concerns about the toxicity of the GO in specific cases, a dosage range and size effects reported in the literature to use it as a nontoxic materials. In view of all these points, an effort has been made to review and emphasize the scope of GO as a biomedical agent for the applications like targeted drug delivery, cancer theranostics, bioimaging and biosensors etc. Further, potential applications along with the future scope and limitations of GO have also been highlighted in this review.

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“…Low detection limit was obtained under the optimal conditions. The specificity of the click chemistry and GO quenching ability revealed low detection limit [28].…”

Section: +mentioning

confidence: 99%

Graphene Oxide for Biomedical Applications

K¹,

Modak²,

Paik³

2017

JNMR

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“…16 In addition, DNA-templated click chemistry reaction can be achieved by CuAAC as the linking tool to trigger azide and alkyne-modied DNA chemical ligation. Due to this merit, DNA-templated click chemistry reaction provides new signal conversion strategies [17][18][19][20] for the detection of alkaline phosphatase activity, single nucleotide polymorphism, and protein, especially Cu 2+ . Nie's group developed a uorescent method for Cu 2+ detection based on DNA-templated click chemistry reaction and magnetic microparticle.…”

Section: Introductionmentioning

confidence: 99%

A unimolecular DNA fluorescent probe for determination of copper ions based on click chemistry

Qin

Yang

et al. 2020

RSC Adv.

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Graphene‐Based Nanotechnology in Neurodegenerative Disorders

Tapeinos

2021

Advanced NanoBiomed Research

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Graphene‐based materials (GBMs) demonstrate unique electrochemical, mechanical, thermal, and optical properties rendering them attractive candidates for numerous biomedical applications. Since graphene's discovery, GBMs have been at the forefront of biomedical research offering innovative solutions for numerous diseases, including neurodegenerative disorders (NDs). There are numerous reviews in which synthesis and functionalization methods of GBMs are discussed. However, this review focuses specifically on the recent research advances of GBMs for NDs, and more specifically, on sensing and therapeutic applications. After a short description of NDs’ main characteristics, significant attention is given to the functionalization strategies used to improve the biomedical properties of GBMs, and recent applications for Alzheimer's disease, Parkinson's disease, Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis. A description of the use of GBMs and neural stem cell technology and known toxicity issues, followed by several limitations that current GBMs need to overcome, completes this review.

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Fluorescent detection of copper(II) based on DNA-templated click chemistry and graphene oxide

Cited by 20 publications

References 44 publications

Graphene Oxide for Biomedical Applications

Graphene Oxide for Biomedical Applications

A unimolecular DNA fluorescent probe for determination of copper ions based on click chemistry

Graphene‐Based Nanotechnology in Neurodegenerative Disorders

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