Fluorescence of nails and hair on Wood's lamp examination in Covid pandemic; undefined effect of Favipiravir in humans

Abstract

Different cutaneous manifestations of coronavirus disease 2019 (COVID-19) has been reported, some of which are due to the adverse effects of the medications. Favipiravir, a broad spectrum antiviral, effective against RNA viruses including influenza and Ebola, is one of the current medications approved for the treatment of Covid-19. 1 Favipiravir selectively inhibits the RNA-dependent RNA polymerase by acting as a guanine analog. It transforms into active phosphoribosylated form in cells, causing chain termination, slowing viral

Fluorescence of ocular surface in a Covid -19 patient after Favipiravir treatment: a case report

“…It is recommended 2 × 1600 mg for the first day and 2 × 600 mg daily for the following four days. A recently published article demonstrated favipiravir induced nail and hair fluorescence [5]. In our literature search, we did not detect any case of ocular surface fluorescence.…”

“…Fourth, a recent study which was conducted by dermatologists reported that the hair and nail fluorescence in Covid-19 patients and they suggested that Favipiravir was the reason for fluorescence. 5 Our patient had a nail fluorescence along with the ocular fluorescence.…”

Fluorescence of Ocular Surface in a Covid -19 Patient After Favipiravir Treatment: a Case Report

“…A recently published article demonstrated favipiravir induced nail and hair uorescence. [5] In our literatüre search, we did not detect any case of ocular surface uorescence. Here in, we reported the rst case of ocular surface uorescence in a patient under favipiravir treatment.…”

Nails and COVID ‐19 – A comprehensive review of clinical findings and treatment

“…It is not yet clear, whether the fluorescence is mainly caused by drug metabolites or by additives of the tablets, such as yellow ferric oxide. 36 …”

“…Green fluorescence has also been observed on the scalp hair made visible by Wood's lamp illumination. It is not yet clear, whether the fluorescence is mainly caused by drug metabolites or by additives of the tablets, such as yellow ferric oxide 36 …”