Flow injection chemiluminescence sensor using core-shell molecularly imprinted polymers as recognition element for determination of dapsone

Lü, Fang; Yang, Jinlong; Sun, Min; Fan, Lulu; Qiu, H.; Li, Xiangjun; Luo, Chuannan

doi:10.1007/s00216-012-6088-2

Cited by 15 publications

(5 citation statements)

References 39 publications

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“…This oxidation peak indicates that the template is becoming a part of the polymeric chain. 21 Both series of successive cyclic voltammograms show an increase in the current intensity corresponding to the growth of the polypyrrole film. Furthermore, the diminution in current in the presence of DDS (as compared with Fig.…”

Section: Resultsmentioning

confidence: 98%

Electrochemical Sensor for Dapsone Using Molecularly Imprinted Polypyrrole Membrane as a Recognition Element

Afkhami

Gomar

Madrakian

2015

J. Electrochem. Soc.

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An electrochemical sensor based on molecularly imprinted polypyrrole membrane is reported for the determination of dapsone (DDS). The sensor was prepared by electropolymerization of pyrrole at a glassy carbon electrode in the presence of DDS as a template. The electropolymerization was performed in the presence of an aqueous solution of 0.1 M HCl, and 0.2 M pyrrole, with and without a template molecule (DDS) at a glassy carbon electrode using cyclic voltammetry. Some of the parameters, important to controlling the performance of the polypyrrole, were investigated and optimized, including the effects of pH, monomer and template concentrations, electropolymerization cycles. The molecularly imprinted film exhibited a high selectivity and sensitivity toward dapsone. The differential pulse voltammetry (DPV) peak current showed a linear dependence on the DDS concentration and a linear calibration curve was obtained in the range 1.0 μM to 110 μM of DDS with a correlation coefficient of 0.998 with a detection limit of 3.0 × 10 −7 M (S/N = 3). The electrode was successfully applied to the determine Dapsone in spiked human serum and urine.

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Section: Resultsmentioning

confidence: 98%

Electrochemical Sensor for Dapsone Using Molecularly Imprinted Polypyrrole Membrane as a Recognition Element

Afkhami

Gomar

Madrakian

2015

J. Electrochem. Soc.

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“…Various analytical techniques have been reported for the determination of Dapsone drug such as chromatography [5,6,7,8], voltammetry [9], and chemiluminescence [10].…”

Section: Introductionmentioning

confidence: 99%

Spectrophotometric Determination of Dapsone Using Charge Transfer Complex Formation Reaction

2020

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A sImple, accurate and sensitive spectrophotometric method for the determination of Dapsone has been developed. The method is based on the charge transfer complex formation reaction of dapsone as n-donors with o-chloranil (o-CA) as π-acceptor in aqueous medium forming colored complex with maximum absorption at 394 nm. Beer's law was obeyed in concentration ranges of 0.125-1.25 µg/ml with molar absorptivity 1.092×10 5 l. mol -1 .cm -1 . The accuracy of the method (average recovery %) was 100.34% and precision (RsD) ≤ 3.91 %. The results show that complex is formed in ratio 1:2 with the stability constant 3.81×10 9 l 2 .mol -2 . The suggested method was applied successfully to determine Dapsone in its pharmaceutical preparation.

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“…For this reason, new indications for dapsone were successively identified, and this drug gained widespread use. Dapsone can be successfully detected by several analytical methods, including high‐performance liquid chromatography (HPLC) , spectrophotometry , flow injection chemiluminescence and electrochemical methods . However, these conventional methods have displayed few disadvantages, such as time consuming and poor chemical/mechanical stability.…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Electrochemical Sensor Based on Modified Reduced Graphene Oxide‐gold Nanoparticles‐polyaniline Nanocomposites Matrix for Dapsone Determination

2019

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This work was designed to develop an electrochemical sensor based on molecular imprinted polyaniline membranes onto reduced graphene oxide (RGO) and gold nanoparticles (AuNPs) modified glassy carbon (GC) electrode for dapsone (DDS) determination. The prepared RGO/AuNPs/PANI‐MIPs nanocomposite was characterized by Ultra‐Violet‐Visible (UV‐Vis), Fourier transform infrared spectroscopy (FT‐IR) and scanning electronic microscopy (SEM) images. The feature of the imprinted electrode was evaluated by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and impedance spectroscopy (IS). Throughout this study several analytical parameters, such as incubation time, pH value, concentration of monomer/template molecules and electro‐polymerization cycles were investigated. Under the optimized conditions, the experimental results showed best analytical performances for DDS detection with a sensitivity of 0.188 Ω/mol L−1, a linear range from 1.0×10−7 M to 1.0×10−3 M and a detection limit of 6.8×10−7 M. The bioanalytical sensor was applied to the determination of dapsone in real samples with high selectivity and recovery.

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Flow injection chemiluminescence sensor using core-shell molecularly imprinted polymers as recognition element for determination of dapsone

Cited by 15 publications

References 39 publications

Electrochemical Sensor for Dapsone Using Molecularly Imprinted Polypyrrole Membrane as a Recognition Element

Electrochemical Sensor for Dapsone Using Molecularly Imprinted Polypyrrole Membrane as a Recognition Element

Spectrophotometric Determination of Dapsone Using Charge Transfer Complex Formation Reaction

Molecularly Imprinted Electrochemical Sensor Based on Modified Reduced Graphene Oxide‐gold Nanoparticles‐polyaniline Nanocomposites Matrix for Dapsone Determination

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