Flexible Nonisothermal Stability Studies

Maulding, H.V.; Zoglio, M.A.

doi:10.1002/jps.2600590312

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Nonisothermal Methods1

Methods For Studying Solid‐state Kinetics1

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2011

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Cited by 34 publications

(13 citation statements)

References 7 publications

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“…Nonisothermal experiments are usually seen in solid-state kinetics, however, they have been previously applied to the study of homogenous kinetics. 19,20 The following relationship can be defined for nonisothermal experiments,…”

Section: Nonisothermal Methodsmentioning

confidence: 99%

Basics and Applications of Solid State Kinetics: A Pharmaceutical Perspective

2006

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Section: Nonisothermal Methodsmentioning

confidence: 99%

Basics and Applications of Solid State Kinetics: A Pharmaceutical Perspective

2006

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“…A linear heating program follows: where, T 0 is the starting temperature, β is the linear heating rate (K/min), and T is the temperature at time, “ t ”. Nonisothermal experiments are usually seen in solid‐state kinetics, however, they have been previously applied to the study of homogenous kinetics 19,20…”

Section: Methods For Studying Solid‐state Kineticsmentioning

confidence: 99%

Evidence that angiogenesis lags behind neuron and astrocyte growth in experience‐dependent plasticity

Wallace

Withers

Farnand

et al. 2011

Developmental Psychobiology

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Bill Greenough's work on the cell biology of information storage suggests that we cannot understand the mechanism of long-term memory without understanding the series of cellular transactions that drive coordinated structural changes in neurons, glia, and blood vessels. Here, we show that after 4 days of differential housing, neuropil of EC cortex has expanded significantly, but the vasculature has not, resulting in a dilution of the blood supply. Significant growth of neurons and astrocytes has been reported within this time period, suggesting expression of synaptic plasticity might involve temporally coordinated genomic responses by both neurons and glia. Given that astrocytes appear to couple neuronal and vascular growth during development, we hypothesize that they may also mediate the onset of angiogenesis in response to neural demand in the EC brain. Further, these results may imply that a neuron's capacity for plasticity could be constrained by the rate of vascular expansion.

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“…Although there are not many detailed physical chemistry studies, numerous publications of an empirical or practical nature described incompatibilities or instabilities or other changes in the solid state (187)(188)(189)(190)(191)(192)(193)(194)(195)(196)(197)(198). As with liquids and semisolids, numerous "extrachemical" parameters change as a function of time in tablets and capsules.…”

Section: Dosage Formsmentioning

confidence: 99%