Flavonoids of Anvillea garcini

Sesquiterpene lactones constitute a large and diverse group of biologically active plant chemical that have been identified in the several plant families.The pharmacological properties of interest involving the sesquiterpene lactones are their antibacterial, antifungal and anti-plusmodial activities.Indeed, assessing the biological activities of the sesquiterpene lactones found in plants and their essential oil is of great medicinal importance because they could potentially be utilized as therapeutic agents for the treatment of such infections.

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“…The small genus Anvillea garcini (tribe Inuleae, subtribe Inulina) is placed in the Inula group 40 . From A. garcini (Burn.)…”

Section: Germacranolides From Anvillea Garcini (Burn) DCmentioning

confidence: 99%

Sesquiterpene Lactones of Iranian Compositae Family (Astraceae); Their Chemical Constituents and Anti-plasmodial Properties of Tehranolide (A.Review)

Rustaiyan¹,

Faridchehr²,

Bakhtiyar³

2017

Orient. J. Chem

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“…Traditionally, the dried plant is crushed, mixed with honey or date and olive oil, and used to treat cold symptoms [4]. Flavonoids and sesquiterpene lactones have been the predominant class of secondary metabolites obtained by phytochemical studies on A. garcinii [5][6][7][8][9][10][11]. Our previous investigations on this plant disclosed the presence of sesquiterpene lactones of the guaianolide-and germacranolidetypes, including the corresponding amino acid adducts, as well as some flavonoids glycosides [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii

et al. 2020

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Two new sesquiterpenoids belonging to the guaiane, 4α,9α,10α-trihydroxyguaia-11(13)en-12,6α-olide (1), and germacrane, 9β-hydroxyparthenolide-9-O-β-D-glucopyranoside (2), classes have been isolated from the leaves of the Saudi medicinal plant Anvillea garcinii along with seven known compounds (3–9). The structures of the new metabolites were elucidated by spectroscopic analysis, including one-dimensional (1D) and two-dimensional (2D) Nuclear Magnetic Resonance (NMR) and high-resolution electrospray ionization mass spectrometry (HR-ESIMS). The antimicrobial properties of 1–9 were screened against seven different pathogenic microbes, and compounds 1–3 showed a potent antifungal activity.

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“…In previous phytochemical studies, parthenolid-9-one, 9α-hydroxyparthenolide, 8α,9α-epoxyparthenolide from A. radiata are reported [14]. Some other germacranolides e.g., 9α-hydroxy-1β,10α-epoxyparthenolide, 9β-hydroxyparthenolide, 9βhydroxy-1β,10α-epoxyparthenolide, cis-partenolid-9-one [9,15,16] and five flavonols glycosides were detected in A. garcinii [17] and thirteen flavonoids from which, four aglycones and nine flavonol glycosides were also isolated from A. radiata [18]. The objective of this study was to compare antioxidant and antimicrobial activities, total phenolic, flavonoid and tannin contents of extracts of A. radiata flowers.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activities, Phenolic, Flavonoid and Tannin Contents and Antibacterial Activity of Anvillea radiata (Coss. & Dur.) Flowers from Southeast Algeria

Mahdjar¹,

Dendougui²,

Hadjadj³

2019

Asian J. Chem.

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Anvillea garcinii subsp. radiata (Coss. & Dur.) are an endemic species of Sahara region especially in Morocco and Algeria. This plant is widely used in traditional medicine. The extraction of phenolic compounds from A. radiata flowers is carried out using solvents of different polarity (chloroform, ethyl acetate, butanol). The yields of extraction from the flowers were 19.34, 0.278, 0.149, 1.750 and 3.308 % for the crude, chloroform, ethyl acetate, butanol and aqueous extracts, respectively. The amount of total phenolics, flavonoids, tannins and in vitro antioxidant and antibacterial properties of extracts of A. radiata flowers. The antioxidant activities were evaluated by measuring the ability of the extracts to scavenge the DPPH, ferric reducing power FRAP and phosphomolybdenum assay. The maximum extractable total phenolics and flavonoids were recorded in ethyl acetate fraction, while the tannins were present in chloroform fraction. Among the five extracts of A. radiata flowers, the maximum DPPH free radical scavenging activity was shown in ethyl acetate and butanol fractions (IC50 = 0.20 ± 0.001 and 0.31 ± 0.004 mg/mL, respectively). The highest activity of FRAP assay and phosphomolybdenum reduction was observed in butanol fraction (358.58 ± 12.55 and 95.09 ± 0.67 mM, respectively). The results were compared with natural and synthetic antioxidants. In antibacterial properties, the chloroform extract has the highest activity. These results implied that these plant extracts may possess health promoting effects and might be potential sources of potent natural antioxidant and antimicrobial.

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Flavonoids of Anvillea garcini

Cited by 22 publications

References 7 publications

Sesquiterpene Lactones of Iranian Compositae Family (Astraceae); Their Chemical Constituents and Anti-plasmodial Properties of Tehranolide (A.Review)

Sesquiterpene Lactones of Iranian Compositae Family (Astraceae); Their Chemical Constituents and Anti-plasmodial Properties of Tehranolide (A.Review)

Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii

Antioxidant Activities, Phenolic, Flavonoid and Tannin Contents and Antibacterial Activity of Anvillea radiata (Coss. & Dur.) Flowers from Southeast Algeria

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