Flavonoides e outras substâncias de Lippia sidoides e suas atividades antioxidantes

Almeida, Macia C. S. de; Alves, Leonardo Alcântara; Souza, Luciana Gregório da Silva; Machado, Luciana Lucas; Matos, Marcos C. de; Oliveira, Maria C. F. de; Lemos, Telma L. G.; Braz‐Filho, Raimundo

doi:10.1590/s0100-40422010000900011

Cited by 38 publications

(25 citation statements)

References 6 publications

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“…The data obtained in the determination of this bioactivity is significant when compared with others obtained in the work of Almeida et al (2010). At a concentration of 100 μg mL −1 (or 1 mg mL −1 as reported), there was an antioxidative activity of 99.5% and an EC 50 of 16.3 μg mL −1 in the ethanolic extract of L. sidoides.…”

Section: Discussionsupporting

confidence: 51%

Secondary metabolites from endophytic fungus from Lippia sidoides Cham.

Ferreira¹,

Santos²,

Soares³

et al. 2017

J. Med. Plants Res.

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Lippia sidoidesCham. (Verbenaceae) is a species native to the Brazilian northeast, widely used in popular medicine. Its leaves were used for the isolation of endophytic fungi and extraction of metabolites. Among them, three were selected according to fungitoxicity tests against the maize phytopathogenic fungus, Curvularia lunata (Wakker). However, the objective of this study was to identify the role of L. sidoides extracts associated with their endophytic fungi, necessary to reduce excess of fungicides applied on the maize crop. Metabolites were evaluated for antioxidant activity by 2.2-diphenyl-1-picrylhydrazyl (DPPH), phenols, total flavonoids and one of it endophytic fungus were evaluated for synergism (Verticilium sp. and plant extracts). The endophytic fungi and plant extracts evaluated for phenolic content ranged from 0.29 ± 0.05 to 96.94 ± 11.86 mgEAG/g, the content of flavonoids from 14.31 ± 1.56 to 192.33 ± 4.58 mgER/g, and antioxidant activity could only be observed for the plant extract with EC 50 81 ± 0.3%. The secondary metabolites identified by HPLC in the plant extract were catechin, quercetin, gallic acid and naringin. Naringenin, catechin, epigallocatechin gallate and quercetin were identified in the extract of the fungi viz. Verticillium sp. and Fusarium sp. Synergistic analysis between a 1:1 proportion of plant and fungal extracts has shown more efficient (79.0%) inhibition of C. lunata. Thus, alternative control of phytopathogenic fungi can be accomplished using plant extracts associated with their endophytic fungi, reducing the excess of fungicides applied on the maize crop.

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Section: Discussionsupporting

confidence: 51%

Secondary metabolites from endophytic fungus from Lippia sidoides Cham.

Ferreira¹,

Santos²,

Soares³

et al. 2017

J. Med. Plants Res.

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“…However, different results were found in this study. 33 Among the extracts of the studied species, those of plants of the genus Buchenavia exhibited the highest capacity to neutralize DPPH, although the chemotypes of L. sidoides had the highest flavonoid contents.…”

mentioning

confidence: 88%

Antioxidant Potential and its Correlation with the Contents of Phenolic Compounds and Flavonoids of Methanolic Extracts from Different Medicinal Plants

Teixeira¹,

vale²,

Almeida³

et al. 2017

Rev. Virtual Quim.

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Resumo: Neste estudo, os extratos metanólicos de dez espécies de plantas medicinais coletadas em Gurupi, Tocantins, Brasil, foram submetidos aos ensaios de neutralização dos radicais ABTS e DPPH, redução do ferro (FRAP) e poder redutor, para investigação do potencial antioxidante. Os resultados revelaram que as plantas avaliadas apresentam pronunciadas atividades antioxidantes, sendo as espécies Buchenavia tetraphylla, Buchenavia tomentosa e Lippia sidoides as que apresentaram as maiores atividades, bem como os maiores teores de compostos fenólicos e de flavonoides. Por meio da determinação dos coeficientes de Person, foi possível observar correlação entre os teores de compostos fenólicos e as atividades antioxidantes perante todos os ensaios. Por outro lado, não foram observadas correlações satisfatórias entre os teores de flavonoides e tais atividades, sugerindo que os compostos fenólicos são os principais contribuintes para o potencial antioxidante apresentado pelos extratos das plantas medicinais estudadas. Palavras-chave: Buchenavia; Lippia sidoides; Ensaios antioxidantes. AbstractIn this study, methanolic extracts of ten species of medicinal plants collected at Gurupi, Tocantins state, Brazil, were subjected to assays of neutralization of ABTS and DPPH radicals, ferric reducing antioxidant power (FRAP), and reducing power to investigate their antioxidant potential. The results revealed that the plants that were investigated exhibited strong antioxidant activities. The species Buchenavia tetraphylla, Buchenavia tomentosa, and Lippia sidoides displayed the highest activities, as well as the largest contents of phenolic compounds and flavonoids. Using Pearson's correlation coefficient, we could observe correlations between the contents of phenolic compounds and the antioxidant activities in all the assays. On the other hand, we could not observe satisfactory correlations between the flavonoid contents and these activities, which suggest that the phenolic compounds provide the main contributions to the antioxidant potential displayed by the medicinal plant extracts that were studied.

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“…Germacrene is an important component identified in the essential oil with significant biological activities. [13]…”

Section: Resultsmentioning

confidence: 99%

Chemical composition of the essential oil and fixed oil Bauhinia pentandra (Bong.) D. Dietr

Almeida¹,

Souza²,

Ferreira³

et al. 2015

Phcog Mag

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Background:Bauhinia pentandrais popularly known as “mororó” and inhabits the Caatinga and Savannah biomes.Objective:This paper reports the chemical composition of the essential and fatty oils of the leaves from B. pentandra.Materials and Methods:The essential oil was obtained by hydrodistillation and the fixed oil by extraction with hexane, followed by saponification with KOH/MeOH, and methylation using MeOH/HCl. The constituents were analyzed by gas chromatography-mass spectrometry.Results:The major constituent of the essential oil was the phytol (58.78% ±8.51%), and of the fatty oil were palmitic (29.03%), stearic (28.58%) and linolenic (10.53%) acids.Conclusion:Of the compounds identified in the essential oil, three are first reported in this species, and this is the first record of the chemical composition of the fixed oil.

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Flavonoides e outras substâncias de Lippia sidoides e suas atividades antioxidantes

Cited by 38 publications

References 6 publications

Secondary metabolites from endophytic fungus from Lippia sidoides Cham.

Secondary metabolites from endophytic fungus from Lippia sidoides Cham.

Antioxidant Potential and its Correlation with the Contents of Phenolic Compounds and Flavonoids of Methanolic Extracts from Different Medicinal Plants

Chemical composition of the essential oil and fixed oil Bauhinia pentandra (Bong.) D. Dietr

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