Antioxidant Potential and its Correlation with the Contents of Phenolic Compounds and Flavonoids of Methanolic Extracts from Different Medicinal Plants

Teixeira, Tallyta Santos; vale, Renata Cássia do; Almeida, Regiamara Ribeiro; Ferreira, Talita Pereira de Souza; Guimarães, Luiz Gustavo L.

doi:10.21577/1984-6835.20170090

Cited by 42 publications

(30 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Correlation analysis indicated that the phenolics and flavonoids were the major reductants of PFF with the correlation coefficients being 0.914 and 0.865, respectively (Table 1s). This indicated that phenolic acids and flavonoids play an important role in Fe 3+ reducing power, which has been reported by many researches (Amarowicz et al, ; Teixeira, do Vale, Almeida, Ferreira, & Guimarães, ). In summary, 50% acetone can be used to enrich antioxidants and reductants from PFF.…”

Section: Resultssupporting

confidence: 73%

HPLC‐QTOF‐MS/MS profiling, antioxidant, andα‐glucosidase inhibitory activities ofPyracantha fortuneanafruit extracts

Wang

et al. 2019

J Food Biochem

View full text Add to dashboard Cite

This study was carried out to optimize the solvent for extracting the antioxidants and α‐glucosidase inhibitors (AGIs) from Pyracantha fortuneana fruit (PFF) and the major chemical components were characterized by HPLC‐QTOF‐MS/MS. The results showed that 50% and 70% acetone (v/v, ml/ml) gave the best extraction efficiency on phenolics and total flavonoids, while 70% acetone and 50% methanol possess better recovery on protein and polysaccharides, respectively. In addition, the 50% and 70% acetone extracts gave the strongest radical scavenging ability and α‐glucosidase inhibitory activity (p > 0.05), but the Fe3+ reducing power of the 50% acetone extract was higher than that of 70% acetone. Correlation analysis indicated that phenolic acids and flavonoids were connected to the antioxidant activity and α‐glucosidase inhibitory activity closely. Moreover, 25 compounds including 7 flavonoids, 6 phenolic acids, 7 organic acids, 3 tannins, 1 terpene, and 1 alkaloid were identified or tentatively identified in the 50% acetone extract. Overall, 50% acetone can be a proper solvent for extracting antioxidants and AGIs from PFF. Practical applications Imbalance between production and clearance of reactive oxygen species (ROS) in the body could induce various chronic diseases. PFF is an edible fruit beneficial to human health; it is reported to be capable of optimizing blood glucose levels and may prevent premature aging. In the present study, PFF was found to be excellent in antioxidant activities and α‐glucosidase inhibitory ability; 50% acetone was found to be the best extraction solvent. In addition, the predominant phytochemical components of the 50% acetone extract were characterized. This study can promote further research of Pyracantha fortuneana in natural functional products, especially in the prevention of type II diabetes and its complication.

show abstract

Section: Resultssupporting

confidence: 73%

HPLC‐QTOF‐MS/MS profiling, antioxidant, andα‐glucosidase inhibitory activities ofPyracantha fortuneanafruit extracts

Wang

et al. 2019

J Food Biochem

View full text Add to dashboard Cite

show abstract

“…The variation in Iron concentration from one tissue to the other is an indication of the difference in its utilization by tissues. These results confirm that the presence of high levels of flavonoids does not always correspond to high antioxidant properties in plants (Teixeira et al, 2017).…”

Section: Effect Of Solvent and Extraction Methods On The Antioxidant supporting

confidence: 72%

“…These results contrast with other studies which showed a positive correlation between flavonoids extracted and their DPPH scavenging activity as well as iron reducing power (Rohman et al, 2010;Abu Bakar et al, 2015;Ojwang et al, 2017). These results show that the presence of high levels of flavonoids does not always correspond to high antioxidant properties in plants as these metabolites have a wide variety of activities (Teixeira et al, 2017).…”

Section: Full Papercontrasting

confidence: 64%

Phytochemical composition and essential mineral profile, antioxidant and antimicrobial potential of unutilized parts of jackfruit

Adan¹,

Ojwang²,

Muge³

et al. 2020

Food Res.

View full text Add to dashboard Cite

The processing of jackfruit (Artocarpus heterophyllus Lam) yields a considerable amount of bio-waste. Accumulation of this waste is considered a health risk because it is a potential source of air and water pollution. Recycling of the unutilized fruit parts, therefore, reduces the quantity and the impact of the bio-waste released to the environment. The purpose of this study was to determine the phytochemical profile, antioxidant and antimicrobial activities of extracts from three fruit parts (peel, fiber and the core) of jackfruit sampled from the coastal region of Kenya. Different extraction techniques and solvents were tested. The highest phenolic and flavonoid content of the peels, fiber and the core were obtained from methanol extracts following a 48-hour incubation. The values were recorded at 17.07±5.16 mg/g, 23.28±4.73 mg/g, and 15.68±3.74 mg/g for the phenolics and 28.55±12.42 mg/g, 35.4±9.53 mg/g and 36.23±2.54 mg/g for the flavonoids, respectively. The highest tannin content was obtained from distilled water extracts following homogenization recorded at 10.82±2.63 mg/g, 10.39±4.10 mg/g and 10.52±1.05 mg/g for peels, fiber and core, respectively. The fiber extracts gave the highest 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity followed by the core at 61.51±29.90% and 51.06±33.39%, respectively. The antioxidant activity was highest for methanol fiber extracts at 61.51±29.90% for DPPH radical scavenging activity and 7.94±4.56 mg/mL for reducing power assay. The best antibacterial activity against Xanthomonas axonopodis pv. manihotis (Xam) was obtained from Ethyl acetate extracts showed. The unutilized jackfruit parts, therefore, are a potential source of natural antioxidants as well as antibacterial, for agriculture and food industry

show abstract

“…TPC values were moderately correlated with TFC (r=0.680, p<0.001), suggested that 46.24% (r 2 ) variation in the TPC was due to TFC. Recent studies have revealed that the TPC was associated with the antioxidant activity (Teixeira et al, 2017;Li et al, 2018). TPC showed a highly significant correlation with FRAP and TEAC values which indicated that the main component of PCs from fractions enabled to transfer their electron to neutralize free radical and to reduce the metal ion.…”

Section: Resultsmentioning

confidence: 94%

Antioxidant activities of methanolic extract and its fractions of Baccaurea racemosa and Macaranga subpeltata leaves

Widodo¹,

Sismindari²,

Asmara³

et al. 2019

Food Res.

View full text Add to dashboard Cite

Oxidative stress, the excessive presence of reactive oxygen species (ROS), is suggested as a basal cause of aging as well as various degenerative and chronic diseases in human. Antioxidants are believed to play a very vital role in the body defense system against ROS. Plant-based antioxidants with their prominence have gained tremendous worldwide interest nowadays. Baccaurea racemosa and Macaraanga subpeltata are among ethnomedical used plants for liver diseases medication which have potential source as natural antioxidants. The aim of the study was to evaluate the antioxidant activities of the methanolic crude extract (CE) and their fractions of the plant’s leaves. Maceration was performed to obtain CE, which then subjected to fractionation using n-hexane, dichloromethane, chloroform, ethyl acetate, and ethanol to obtain fractions of hexane fraction (HF), dichloromethane (DF), chloroform (CF), ethyl acetate (EAF), and ethanol fractions (EF), respectively. The CE and all fractions included water fraction (WF) and residue (R) were examined for its total phenolic contents, total flavonoid contents, and antioxidant activities using various in vitro assay. In general, EAF demonstrated as the best solvent for the extracting phenolic compounds with higher antioxidant activity. The CE and its fractions of M. subpeltata contained higher of TPC and TFC, also demonstrated higher antioxidant capacity, than that B. racemosa. The phenolics compounds were responsible for the antiradical properties. The EAF of M. subpeltata was scavenging those radicals better than that of L-(+)ascorbic acid as a positive control. The high antioxidant activities and phenolics contents make both the plant extracts to be developed as a food supplement.

show abstract

Antioxidant Potential and its Correlation with the Contents of Phenolic Compounds and Flavonoids of Methanolic Extracts from Different Medicinal Plants

Cited by 42 publications

References 26 publications

HPLC‐QTOF‐MS/MS profiling, antioxidant, andα‐glucosidase inhibitory activities ofPyracantha fortuneanafruit extracts

HPLC‐QTOF‐MS/MS profiling, antioxidant, andα‐glucosidase inhibitory activities ofPyracantha fortuneanafruit extracts

Phytochemical composition and essential mineral profile, antioxidant and antimicrobial potential of unutilized parts of jackfruit

Antioxidant activities of methanolic extract and its fractions of Baccaurea racemosa and Macaranga subpeltata leaves

Contact Info

Product

Resources

About