Flavonoid compounds identified in <i>Alchemilla l.</i> species collected in the North-eastern Black sea region of Turkey

Abstract

This study identified flavonoid glycosides in species of the genus Alchemilla, A. procerrima, A. stricta, A. hirtipedicellata and A. sericata. A. procerrima is an endemic species for Turkey. After detailed investigation, flavonoid compounds of the species were identified for the first time. In this study, flavonoid compounds were determined by using two different chromatography techniques, TLC and HPLC. The following flavonoid compounds were identified from the Alchemilla species studied. They are as follows: orientin ( were also identified for the first time in this study. Rutin (quercetin-3-O-rutinoside) and the flavonoid glycoside, shown as Rf 2 were found in all species. Quercitrin and isoquercetin were determined in all analysed species but A. procerrima. Hyperoside was identified in all species except for A. stricta. Vitexin was determined only in A.stricta. Orientin was determined in A. procerrima and A. stricta, but could not be determined in A. sericata and A. hirtpedicellata. Unknown flavonoid with Rf 1 and Rf 3 were determined outside of A. sericata. Description of these compounds in Turkish Alchemilla plants for the first time should be viewed as a discovery of an important chemosystematic feature.

Phenolic Composition, Anti‐Inflammatory, Antioxidant, and Antimicrobial Activities of Alchemilla mollis (Buser) Rothm.

“…Alchemilla species (Rosaceae) has been used for medicinal properties for centuries, and this genus is quite common all over the world. Especially Alchemilla vulgaris ‘Lady's mantle’ is represented as ‘Herba Alchemillae’ in the European Pharmacopoeia . Alchemilla is used for astringent, anti‐hemorrhoidal, and anti‐diarrheal activity.…”

“…Especially Alchemilla vulgaris 'Lady's mantle' is represented as 'Herba Alchemillae' in the European Pharmacopoeia. [8][9] Alchemilla is used for astringent, anti-hemorrhoidal, and anti-diarrheal activity. In traditional medicine, infusion of this plant has been used externally for treatment of stomatitis and wound healing.…”

Bioassay Guided Isolation of Active Compounds from Alchemilla barbatiflora Juz.

“…Among the isolated compounds; catechin was previously isolated from A. mollis [12] and A. speciosa [36], tiliroside was isolated from A. achtarowii [13] and A. mollis [37], while miquelianin and guaiaverin were isolated from A. xanthochlora [14,38] and A. achtarowii [13]. As well as hyperoside was reported to be present in A. procerrima, A. hirtipedicellata, A. sericata [11]. However, catechin dimer; procyanidin B3 is being reported for the first time from the genus Alchemilla.…”

Herbal teas as a rich source of phenolic compounds

“…Moreover, calendula has healing and antiseptic properties with actions that are sudorific and analgesic, affect the bile duct, are antiinflammatory, antiviral and anti-emetic, and tone the skin with vasodilation [15]. Kaya et al (2012) also indicated that flavonoids captured the interest of scientists from many different disciplines because of their structural diversity, biological and ecological significance in systematic, and health-promoting and anti-cancer properties [16]. Yarrow (Achillea millefolium L.) also traditionally has been used as an abortifacient, emmenagogue, contraceptive, and for stimulating uterine contractions.…”