First case of Nocardia amamiensis pulmonary infection in Mexico

Abstract

We report a case of Nocardia amamiensis pulmonary infection in a 43-year-old immunocompromised woman. The patient was treated with imipenem/cilastatin and trimethoprim/sulfamethoxazole and had a favourable outcome. It is important that laboratories perform species identification to understand the epidemiology and susceptibility patterns of the different Nocardia spp.

Pathogenic Nocardia amamiensis infection: A rare case report and literature review

“…N. amamiensis , identified as a novel species, was first isolated from a sugarcane field in Japan in 1997 by Yamamura H. et al [ 8 ]. However, only six cases of nocardiosis caused by N. amamiensis have been reported to date, with detailed descriptions available for just three of those cases [ 9 , 10 , 13 ]. Furthermore, previous reports or studies on the epidemiology of nocardiosis have rarely included cases caused by N. amamiensis .…”

“…It appears that patients with underlying diseases or those undergoing treatment with immunosuppressive agents are more susceptible to N. amamiensis pulmonary infection. The first report of pulmonary infection caused by N. amamiensis was published by Martinez-Gamboa A. et al, in 2016 [ 10 ]. The current case represents only the fourth reported case and is the first to be reported in an immunocompetent patient without structural pulmonary disease.…”

“…In 2007, a novel species called Nocardia amamiensis was discovered in the soil of a sugarcane field in Japan [ 8 ]. o date, only six cases of N. amamiensis infection have been reported [ [9] , [10] , [11] , [12] , [13] ]. However, no cases have been reported in patients with normal immune function and without structural pulmonary disease.…”

Diversity, antimicrobial activity, and susceptibility of culturable soil actinobacteria isolated from Sichang Island

“…bhagyanarayanae and N. amamiensis were the most frequent species found on Sichang Island. Infection caused by N. amamiensis is rare, with only two ocular and two pulmonary infections previously reported [26,27]. In 2016, Martinez-Gamboa et al reported pulmonary infection caused by N. amamiensis in Mexico.…”

“…In 2016, Martinez-Gamboa et al reported pulmonary infection caused by N. amamiensis in Mexico. The strain was susceptible to trimethoprim-sulfamethoxazole, amoxicillin/clavulanic acid, imipenem, and amikacin [27]. Reddy et al reported two strains of N. amamiensis isolated from ocular infection [26].…”