First Carpometacarpal Joint Denervation for Primary Osteoarthritis: Technique and Outcomes

Donato, Daniel P.; Abunimer, Abdullah M.; Abou‐Al‐Shaar, Hussam; Willcockson, James; Frazer, Leah; Mahan, Mark A.

doi:10.1016/j.wneu.2018.11.061

Cited by 19 publications

(24 citation statements)

References 15 publications

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“…Three studies reported changes in pain following denervation of the CMC joint using the VAS or NRS score. 14 , 16 , 19 The baseline pain scores and postoperative pain scores from these studies were pooled and analyzed using a 2-sided paired t test (α = 0.05). 14 , 16 , 19 This group had a combined sample size of 80 patients (61 women and 19 men) and 84 thumbs with a mean age (±SD) of 62.53 ± 2.03 years.…”

Section: Resultsmentioning

confidence: 99%

“… 14 , 16 , 19 The baseline pain scores and postoperative pain scores from these studies were pooled and analyzed using a 2-sided paired t test (α = 0.05). 14 , 16 , 19 This group had a combined sample size of 80 patients (61 women and 19 men) and 84 thumbs with a mean age (±SD) of 62.53 ± 2.03 years. The average follow-up time within this cohort was 12 months after surgery (range, 7-82 months).…”

Section: Resultsmentioning

confidence: 99%

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Denervation as a Treatment for Arthritis of the Hands: A Systematic Review of the Current Literature

Zhu

Chin

Sarraj

et al. 2021

Hand (New York, N,Y.)

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Joint denervation has been proposed as a less invasive option for surgical management of hand arthritis that preserves joint anatomy while treating pain and decreasing postoperative recovery times. The purpose of this systematic review was to investigate the efficacy and safety of surgical joint denervation for osteoarthritis in the joints of the hand. EMBASE, MEDLINE, and PubMed databases were searched from January 2000 to March 2019. Studies of adult patients with rheumatoid arthritis or osteoarthritis of the hand who underwent joint denervation surgery were included. Two reviewers performed the screening process, data abstraction, and risk of bias assessment (Methodological Index for Non-Randomized Studies). This review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was registered with PROSPERO (#125811). Ten studies were included, 9 case series and 1 cohort study, with a total of 192 patients. In all studies, joint denervation improved pain and hand function at follow-up (M = 36.8 months, range = 3-90 months). Pooled analysis of 3 studies on the first carpometacarpal joint showed a statistically significant ( P < .001) reduction in pain scores from baseline (M = 6.61 ± 2.03) to postoperatively (M = 1.69 ± 1.27). The combined complication rate was 18.8% (n = 36 of 192), with neuropathic pain or unintended sensory loss (8.8%, n = 17 of 192) being the most common. This review suggests that denervation may be an effective and low-morbidity procedure for treating arthritis of the hand. Prospective, comparative studies are required to further understand the outcomes of denervation compared with traditional surgical interventions.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Denervation as a Treatment for Arthritis of the Hands: A Systematic Review of the Current Literature

Zhu

Chin

Sarraj

et al. 2021

Hand (New York, N,Y.)

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“…Eight articles evaluated the results of a total of 194 patients with 200 first carpometacarpal joint denervation with an average follow-up of 2.8 years. Four studies [36][37][38][39] were eligible for meta-analysis on pain reduction. The mean difference for the visual analogue scale score for pain improved 5.38 points (95 percent CI, 3.54 to 7.21).…”

Section: Denervation Of the Carpometacarpal Joint Of The Thumbmentioning

confidence: 99%

Denervation of the Joints of the Hand and Wrist: Surgical Techniques and a Systematic Review with Meta-Analysis

Tieman

Duraku

Oest

et al. 2021

Plastic &Amp; Reconstructive Surgery

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hronic pain of the joints of hand and wrist can be debilitating and lead to significant impairment in daily life. Symptomatic hand and wrist osteoarthritis alone affects approximately 5 percent of all adults worldwide and has a prevalence as high as 20 percent in elderly patients. 1 First-line treatment for chronic hand and wrist joint pain consists of analgesics, hand therapy, splints, corticosteroid injections, or a combination of these techniques. [2][3][4] If these nonoperative measures are insufficient, more rigorous surgical secondline treatments are available such as arthrodesis, resection, or joint replacement. 5,6 All these procedures have a lengthy rehabilitation period and can decrease the range of motion of the affected joints.An elegant intermediate solution can be denervation of the joint. Joint denervation has been described for several joints, starting in 1933 for the hip joint by Tavernier. 7 Wilhelm popularized the joint denervation technique for the hand and wrist. 8 The focus of the treatment lies in the dissection of the articular branches innervating

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“…Grip strength has been widely and routinely evaluated for decades in rheumatology as a functional measure in patients with joint inflammation, osteoarthritis or other musculoskeletal diseases (e.g. Bijlsma et al, 1987;Pincus and Callahan, 1992;Spacek et al, 2004;Lee et al, 2013a;Donato et al, 2018;Beaudart et al, 2019), and remarkably, it has long been known to correlate with pain (Callahan et al, 1987;Fraser et al, 1999;Overend et al, 1999;Lee et al, 2013b;LoRusso et al, 2018). Grip strength assessment in experimental animals, however, was developed for a very different purpose: to assess the effects of muscle relaxants and to test drug-induced toxicity (Tilson, 1990;Nevins et al, 1993).…”

Section: Grip Strength Deficits As a Measure Of Pain-induced Functionmentioning

confidence: 99%

The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?

González‐Cano

Montilla-García

Ruiz-Cantero

et al. 2020

Neuroscience & Biobehavioral Reviews

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First Carpometacarpal Joint Denervation for Primary Osteoarthritis: Technique and Outcomes

Cited by 19 publications

References 15 publications

Denervation as a Treatment for Arthritis of the Hands: A Systematic Review of the Current Literature

Denervation as a Treatment for Arthritis of the Hands: A Systematic Review of the Current Literature

Denervation of the Joints of the Hand and Wrist: Surgical Techniques and a Systematic Review with Meta-Analysis

The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?

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