Fingerroot (Boesenbergia pandurata) : A Prospective Anticancer Therapy

Abstract

Beside as a spice in Indonesian cooking, Fingerroot (Boesenbergia pandurata) regularly is used as a mixture of herbal medicine. Scientifically, the phytochemical content of the fingerroot rhizome showed some therapeutical effects such as antibacterial, anti-inflammatory, anti or pro-oxidant, and also anticancer. In this article, we summarize some studies especially about anticancer activity of fingerroot and its constituent coumpound. We found that fingerroot is capable of inhibiting various pathways of cell physiology processes. One potential pathway to be inhibited by fingerroot is Poly (ADP-ribose) polymerase (PARP) which has role in apoptotic induction. In the future, it is necessary to purify the extract to obtain maximum efficacy and also formulation studies of fingerroot will be interesting to do to.

Earliest curry in Southeast Asia and the global spice trade 2000 years ago

“…Medicinal uses of galangal are recorded in Sanskrit texts that date back to 600 CE ( 6 ). The other two Zingiberaceae species—fingerroot ( B. rotunda ) and sand ginger ( K. galanga )—are used today as seasonings and herbal medicines and also have a long history of utilization in Southeast Asia ( 48 , 49 ).…”

Model Desain Apotik Hidup bagi Keberlanjutan Pemanfaatan Pengolahan Sampah Organik Rumah Tangga di Desa Ciangsana, Kabupaten Bogor

“…Obat aphrodisiak, mengatasi ganguan kolik (Taweechaisupapong et al, 2010), bahan sauna (Silalahi et al, 2015a) sebagai campuran minuman tonik bagi ibu pasca melahirkan (Silalahi et al, 2015b), anti-HIV-1 PR, anti-inflammatori dan anti oksidatif (Kim et al, 2013;Chahyadi et al, 2014), analgesik, anti kanker (Nurrachma et al, 2018), dan anti obesitas (Kim et al, 2013), serta dikenal sebagai antimikroba karena mengahambat pertumbuhan fungi, khamir dan bakteria (Chahyadi et al, 2014). 9…”