Fine‐Needle Aspiration of the Spleen as an Aid in the Diagnosis of Splenomegaly

O'Keefe, Deborah A.; Couto, C. Guillermo

doi:10.1111/j.1939-1676.1987.tb01997.x

Cited by 62 publications

(48 citation statements)

References 9 publications

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“…Therefore, ultrasonographic findings must be correlated with the history, clinical signs, and laboratory examinations to establish a differential diagnosis. The ultrasound-guided biopsy by aspirate or tissue-core is very helpful to determine uniform and nodular splenomegaly (O'KEEFE; COUTO, 1987;NYLAND, 2002;THRALL, 2007;CHRISTENSEN et al, 2009). No complications have been reported with splenic aspirates or tissue-core exam if the coagulation parameters are normal (NYLAND, 2002).…”

Section: Resultsmentioning

confidence: 99%

Splenic lesions observed in 71 splenectomized dogs: a retrospective study

Silva

Santis

Headley

et al. 2016

SCA

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The spleen of dogs is frequently affected by disorders that vary from local and systemic origin. The difficulty in associating clinical and gross findings contributes for the choice of total splenectomy as the main treatment, leading to an impairment of the immune and hematopoietic functions. The aim of this study was to evaluate the pathological findings in the spleen of splenectomized dogs during 2008 to 2014 at a Veterinary Teaching Hospital. From the 71 cases analyzed, 97,2% (69/71) of the dogs were submitted to total splenectomy and 2,8% (2/71) to partial splenectomy. In 45 (63.4%) of these cases, the histopathological diagnosis was non-neoplastic alterations; only 36.6% (26/71) had a splenic neoplasia. The main non-neoplastic lesions observed were nodular hyperplasia 24.4% (11/45), infarction 22.3% (10/45), and hematoma 20% (9/45). The most frequent tumors were hemangiosarcoma 50% (13/26), histiocytic sarcoma 23% (6/26), and lymphoma 11.5% (3/26). The clinical methods used to diagnose splenic lesions were ultrasonography 88% (63/71), radiography 2.8% (2/71) and exploratory laparotomy 4.2% (3/71). In 4.2% (3/71) of these cases, the splenic changes were observed during therapeutic ovariohysterectomy. Results of the present study showed a prevalence of benign disorders in the spleen of splenectomized dogs associated with a high incidence of total splenectomy performed, indicating a difficulty in recognizing the different lesions that can affect the spleen by the veterinarian medical. Key words: Dogs. Histopathological findings. Splenic disorders. ResumoO baço de cães é frequentemente afetado por alterações locais ou de origem sistêmica. A dificuldade em associar achados clínicos e macroscópicos contribuem para a escolha da esplenectomia total com principal tratamento, levando a um comprometimento das funções imune e hematopoiética. O principal objetivo deste estudo foi avaliar os achados patológicos no baço de cães esplenectomizados durante 2008 a 2014 em um Hospital Escola Veterinário. Dos 71 casos analisados, 97,2% (69/71) dos cães foram submetidos à esplenectomia total e 2,8% (2/71) à esplenectomia parcial. Em 45 (63,4%) casos, o diagnóstico histopatológico foi de alterações não-neoplásicas; somente 36,6% (26/71) tinham neoplasia esplênica. As principais alterações não-neoplásicas observadas foram hiperplasia nodular 24,4% (11/45), infarto 22,3% (10/45) e hematoma 20% (9/45). Os tumores mais frequentes foram

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Section: Resultsmentioning

confidence: 99%

Splenic lesions observed in 71 splenectomized dogs: a retrospective study

Silva

Santis

Headley

et al. 2016

SCA

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“…Complications did not develop at all after FNAs in many studies, whilst other studies reported rare mild complications, such as pain, small haematomas, minimal bleeding from the local site and haematuria (Hager et al 1985, O ' keefe & Couto 1987, Léveillé et al 1993, Bonfanti et al 2004. Two mortalities were reported in each of two abstract reports on 307 feline liver FNAs, and 600 canine liver FNAs (Menard & Papageorges 1996, Papageorges 1996.…”

Section: Risk Versus Benefit Of Fnamentioning

confidence: 99%

Fine needle aspiration of abdominal organs: a review of current recommendations for achieving a diagnostic sample

Liffman

Courtman

2017

J of Small Animal Practice

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With the improved accessibility to ultrasound, fine needle aspiration of abdominal organs is now performed frequently in many veterinary practices. Despite this, there are many ‘unknowns’ as to the best method to produce a high‐quality sample. This report begins by highlighting recent literature on the risks and benefits of abdominal fine needle aspiration. It follows with recommendations about the equipment and method best suited to the procedure, including needle and syringe size and aspiration versus non‐aspiration techniques. Various smear preparations and laboratory submission requirements are also discussed. The final aspect of the review more specifically discusses fine needle aspiration of specific abdominal organs: the liver, kidney, spleen, pancreas, urinary bladder, prostate and abdominal lymph nodes.

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“…Evidence of spread was hard to determine because of the large size of the tumour. Pre-operative cytological samples were not taken because of limitations in overall correspondence between the cytological and histopathological findings for liver and splenic nodular masses (O'Keefe and Couto 1987;Kuntz et al 1997;Wang et al 2004;Bellegeer et al 2007). Therefore, apart from stopping the bleeding and providing a palliative relief of discomfort, the surgery was also utilised as a diagnostic tool.…”

Section: Discussionmentioning

confidence: 99%

Splenic malignant mesenchymoma in a dog - immunophenotypic features and clinicopathological ramifications: a case report

Dokic¹,

Pirog²,

Benák³

et al. 2014

Vet. Med. - Czech

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ABSTRACT:A 13-year-old spayed bitch was referred for evaluation of an abdominal distension with a palpable, continuously growing mass. Abdominal ultrasonography revealed a 30 × 20 cm mass directly connected to the spleen. Surgical exploration confirmed the sonographic diagnosis with adhesions to the omentum and the liver. Pathohistological samples revealed well differentiated adipose tissue and variably differentiated collagenous and myxomatous tissue. Immunohistochemically, vimentin and in some regions alpha smooth muscle actin were expressed indicating smooth muscle differentiation. The results support the diagnosis of a malignant mesenchymoma composed of liposarcoma, mixosarcoma and leiomyosarcoma. No local recurrence or metastasis occurred during a nine month follow-up. So far, only two pathological retrospective studies describing the common prevalence and properties of canine splenic malignant mesenchymomas were found in the literature. However, this rare tumor entity has to be considered as a differential diagnosis in cases of large splenic masses.

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Fine‐Needle Aspiration of the Spleen as an Aid in the Diagnosis of Splenomegaly

Cited by 62 publications

References 9 publications

Splenic lesions observed in 71 splenectomized dogs: a retrospective study

Splenic lesions observed in 71 splenectomized dogs: a retrospective study

Fine needle aspiration of abdominal organs: a review of current recommendations for achieving a diagnostic sample

Splenic malignant mesenchymoma in a dog - immunophenotypic features and clinicopathological ramifications: a case report

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